Ampd3
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Official Full Name
adenosine monophosphate deaminase 3
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Synonyms
AMP deaminase 3; Ampd;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
- N
- Involved Pathway
- Protein Function
- Interacting Protein
Ampd3 involved in several pathways and played different roles in them. We selected most pathways Ampd3 participated on our site, such as Purine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ampd3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Purine metabolism | PDE11A;NT5C1B;NT5C1B-RDH14;PDE6A;POLR3B;CANT1;NPR1A;PRPS1L1;ADSSL1 |
Metabolic pathways | PAFAH1B1;ATP6V1D;HYI;PDXKA;PGM2;ATP5C1;CYP4A10;KYNU;MECR |
Ampd3 has several biochemical functions, for example, AMP deaminase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ampd3 itself. We selected most functions Ampd3 had, and list some proteins which have the same functions with Ampd3. You can find most of the proteins on our site.
Function | Related Protein |
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AMP deaminase activity | AMPD3B;AMPD3;AMPD1;AMPD2 |
metal ion binding | ZFP1;ZDHHC14;AGFG1A;MAT2AL;PRDM9;OVOL2;ING5B;ZNF165;LHX6 |
Ampd3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ampd3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ampd3.
katG; ALB
- Q&As
- Reviews
Q&As (14)
Ask a questionAs of now, there are no known ongoing clinical trials specifically targeting AMPD3 protein. However, it is possible that research is being conducted in this area, and it is always recommended to check clinical trial registries or consult with healthcare professionals for the most up-to-date information on ongoing trials.
Since AMPD3 deficiency is a rare condition with limited understanding, there are no specific experimental treatments or therapies currently being explored. However, as research progresses, there may be potential for the development of targeted therapies in the future. Consulting with healthcare professionals or geneticists who specialize in this area can provide the most up-to-date information on relevant research and potential treatment options.
It may be helpful to consult with healthcare professionals or geneticists who specialize in genetic and metabolic disorders for more information about AMPD3 protein deficiency. Additionally, reputable scientific literature, genetics databases, and patient advocacy groups may offer valuable resources on this topic.
AMPD3 protein is expressed in various tissues and cell types in the body. It is found in high levels in skeletal muscle, heart muscle, liver, and brain. However, lower levels of expression can also be detected in other tissues, such as kidney, lung, and adipose tissue.
A deficiency of AMPD3 protein is associated with an increased risk of certain metabolic disorders and can lead to abnormalities in purine metabolism. However, it is important to note that AMPD3 deficiency is a rare condition and the exact consequences of its deficiency are still being studied.
Yes, there are genetic variations and mutations associated with AMPD3 protein. Single nucleotide polymorphisms (SNPs) have been identified in the AMPD3 gene, which can lead to altered enzyme activity or expression levels. These genetic variations have been linked to certain conditions, such as exercise-induced fatigue or muscle disorders. Additionally, rare mutations in the AMPD3 gene have been found in individuals with a condition called adenosine monophosphate deaminase deficiency, which affects muscle function.
Targeting AMPD3 protein could have therapeutic implications in various diseases or conditions. For instance, since AMPD3 plays a role in purine metabolism, modulating its activity could be beneficial in the treatment of certain forms of cancer, where altered purine metabolism is observed. Inhibiting AMPD3 could potentially limit the production of nucleotides that cancer cells require for their rapid proliferation. On the other hand, the activation of AMPD3 could be explored as a therapeutic approach in neurodegenerative disorders or metabolic diseases, where energy metabolism or cellular stress response is compromised.
Currently, there are no known genetic disorders specifically associated with AMPD3 protein deficiency. However, variations in the AMPD3 gene have been identified in some individuals, and further research is needed to understand the potential implications of these variations on health and disease.
Conducting research on AMPD3 protein or its related disorders typically involves a combination of laboratory experiments, genetic analysis, and literature reviews. If you are a student or researcher, you can access scientific databases, such as PubMed and Scopus, to search for relevant articles and studies. Additionally, consulting with experts in the field, attending scientific conferences, and joining relevant professional societies or research groups may provide further opportunities for research and collaboration.
While the primary function of AMPD3 protein is related to purine metabolism, recent studies have suggested additional roles for AMPD3. It has been proposed to have functions in energy balance, cellular stress response, and mitochondrial function. However, further research is required to fully unravel the multifaceted functions of AMPD3 protein.
Currently, there are limited known inhibitors or activators specifically targeting AMPD3 protein. However, there are some compounds that have been shown to modulate AMPD activity in general, which includes AMPD3. For example, certain small molecules, such as PSPC1, have been found to inhibit AMPD activity. Additionally, AMP analogs or activators, such as AICAR (5-aminoimidazole-4-carboxamide ribonucleotide), can activate AMPD enzymes, including AMPD3. Further research is needed to identify more specific and selective inhibitors or activators for AMPD3.
While much of the research on AMPD3 protein has focused on its role in metabolism, there is emerging evidence suggesting its involvement in aging or longevity. Studies have shown that AMPD3 expression and activity decline with age, particularly in tissues like skeletal muscle and heart. Additionally, strategies that activate AMPD3, such as caloric restriction or exercise, have been associated with increased lifespan in some organisms. However, more research is needed to fully understand the relationship between AMPD3 and aging.
Yes, the levels of AMPD3 protein can be altered in certain conditions or diseases. For example, exercise or physical activity has been shown to increase the expression of AMPD3 in skeletal muscle. On the other hand, some studies have reported associations between alterations in AMPD3 expression and conditions such as cancer, cardiovascular disease, and neurodegenerative disorders. However, more research is needed to fully understand the implications of these associations.
Yes, the expression of AMPD3 protein is regulated. It can be influenced by various factors, including transcriptional and post-transcriptional mechanisms. For example, certain signaling pathways and transcription factors can regulate the expression of the AMPD3 gene. Additionally, microRNAs or other non-coding RNAs can interact with the messenger RNA (mRNA) of AMPD3 and affect its translation into protein.
Customer Reviews (5)
Write a reviewIts utilization in this technique has allowed for precise visualization and determination of protein structures with remarkable clarity and resolution.
Its excellent performance in this application makes it a valuable asset in immunoassays and other biochemical studies.
Ampd3 protein has exhibited remarkable performance in Western Blotting experiments.
Ampd3 protein has proved to be an invaluable tool in protein electron microscopy structure analysis.
The reliable and high-quality results obtained using Ampd3 protein make it an excellent choice for researchers studying protein structures.
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