Description : |
Cyclin-dependent kinase 15, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein, Cell division protein kinase 15, Serine/threonine-protein kinase ALS2CR7, Serine/threonine-protein kinase PFTAIRE-2; Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'. Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. |
Source : |
Insect cell |
Species : |
Human |
Tag : |
GST/Flag |
Form : |
Liquid |
Protein Length : |
M1-W435/M1-S341 |
Endotoxin : |
< 0.01 EU/μg of the protein |
Purity : |
70% |
Stability : |
Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade |
Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : |
Supplied as sterile 25 mM HEPES (pH 7.5), 500 mM NaCl, 5% glycerol, 1 mM DTT, 20 mM GSH. |
Shipping : |
It is shipped out with blue ice. |