| Description : |
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
90.3 kDa |
| AA Sequence : |
MHKHQHCCKCPECYEVTRLAALRRL EPPGYGDWQVPDPYGPGGGNGASAG YGGYSSQTLPSQAGATPTPRTKAKL IPTGRDVGPVPPKPVPGKSTPKLNG SGPSWWPECTCTNRDWYEQVNGSDG MFKYEEIVLERGNSGLGFSIAGGID NPHVPDDPGIFITKIIPGGAAAMDG RLGVNDCVLRVNEVDVSEVVHSRAV EALKEAGPVVRLVVRRRQPPPETIM EVNLLKGPKGLGFSIAGGIGNQHIP GDNSIYITKIIEGGAAQKDGRLQIG DRLLAVNNTNLQDVRHEEAVASLKN TSDMVYLKVAKPGSLHLNDMYAPPD YASTFTALADNHISHNSSLGYLGAV ESKVSYPAPPQVPPTRYSPIPRHML AEEDFTREPRKIILHKGSTGLGFNI VGGEDGEGIFVSFILAGGPADLSGE LRRGDRILSVNGVNLRNATHEQAAA ALKRAGQSVTIVAQYRPEEYSRFES KIHDLREQMMNSSMSSGSGSLRTSE KRSLYVRALFDYDRTRDSCLPSQGL SFSYGDILHVINASDDEWWQARLVT PHGESEQIGVIPSKKRVEKKERARL KTVKFHARTGMIESNRDFPGLSDDY YGAKNLKGQEDAILSYEPVTRQEIH YARPVIILGPMKDRVNDDLISEFPH KFGSCVPHTTRPRRDNEVDGQDYHF VVSREQMEKDIQDNKFIEAGQFNDN LYGTSIQSVRAVAERGKHCILDVSG NAIKRLQQAQLYPIAIFIKPKSIEA LMEMNRRQTYEQANKIYDKAMKLEQ EFGEYFTAIVQGDSLEEIYNKIKQI IEDQSGHYIWVPSPEKLTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
