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Official Full Name Dlg4 discs, large homolog 4 (Drosophila)
Synonyms DLG4; discs, large homolog 4 (Drosophila); disks large homolog 4; SAP-90; PSD-95 beta; PSD-95 alpha 2b; discs large homolog 4; synapse-associated protein 90; postsynaptic density protein 95; Dlgh4; PSD95; SAP90; PSD-95; SAP90A;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DLG4-152H Recombinant Human DLG4 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DLG4-159H Recombinant Human DLG4 protein, GST-tagged Wheat Germ GST
    Human DLG4-18H Recombinant Human DLG4 protein, His-tagged E.coli His
    Human DLG4-31002TH Recombinant Human DLG4 Wheat Germ N/A
    Human DLG4-6910HCL Recombinant Human DLG4 293 Cell Lysate HEK293 N/A
    Human DLG4-902H Recombinant Human DLG4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Dlg4-2576M Recombinant Mouse Dlg4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse DLG4-4622M Recombinant Mouse DLG4 Protein Mammalian Cell His
    Rat DLG4-1881R Recombinant Rat DLG4 Protein Mammalian Cell His

    DLG4 involved in several pathways and played different roles in them. We selected most pathways DLG4 participated on our site, such as ARMS-mediated activation, Activation of Ca-permeable Kainate Receptor, Activation of Kainate Receptors upon glutamate binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ARMS-mediated activation FRS2A; SPNA1; DLG4; PAQR3B; KBTBD7; FGF8B; DUSP2; NRG2A; PSMD14; SPTBN1
    Activation of Ca-permeable Kainate Receptor DLG4; DLG1L; DLG3; NCALDA
    Activation of Kainate Receptors upon glutamate binding DLG1L; NCALDA; GNB5; DLG3; DLG4
    Activation of NMDA receptor upon glutamate binding and postsynaptic events PDPK1A; AKAP9; ADCY3; DLG4; CREB1; ADCY1; NETO2; CREB1B; ADCY8; CAMKK1B
    Axon guidance ROCK1; RHOGA; SPRED2; EFNA2A; NTN1B; FES; EFNA1; RAC3; MAPK3; SCN3A
    CREB phosphorylation through the activation of CaMKII NETO2; AKAP9; SLC14A2; NEFLB; DLG4; CREB1B
    CREB phosphorylation through the activation of Ras DLG4; NEFLB; SLC14A2; PDPK1A; AKAP9
    Cocaine addiction CREB3L1; GNAI2; RGS9; GNAI3; CREB3L3; GNAS; BDNF; CDK5; DRD2; RELA

    DLG4 has several biochemical functions, for example, D1 dopamine receptor binding, P2Y1 nucleotide receptor binding, PDZ domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLG4 itself. We selected most functions DLG4 had, and list some proteins which have the same functions with DLG4. You can find most of the proteins on our site.

    Function Related Protein
    D1 dopamine receptor binding ATP1A3; DLG4; CAV2; ARRB2; AGTR1A; DRD3; GNAS; PTPN11
    P2Y1 nucleotide receptor binding DLG4
    PDZ domain binding ERC1; EXOC4; TBC1D10A; CLCN3; CFTR; KIDINS220B; LNX2; FZD7; LIN7C; ATP2B1A
    acetylcholine receptor binding APP; DLG4; RIC3; NRXN1; JAK2; RER1; RAPSN; KCNS1; UBXN2A
    beta-1 adrenergic receptor binding MAGI2; DLG4
    guanylate kinase activity GUK1; MPP3; DLG4B; DLG4; GUK1B; DLG1; DLG1L; CARD11; GUK1A; MPP1
    ionotropic glutamate receptor binding CACNG2; GNAS; DRD2; DLG3; FLOT2; DLG4B; ADRB2; SHANK3; SHANK2; RAB4A
    kinase binding PIP5K1A; TRADD; PRPSAP1; PER3; PER1; DLG3; HSP90AB1; PPP1R9B; TOLLIP; ATF5
    neuroligin family protein binding NRXN2; NRXN3; DLG4; NRXN1
    protein C-terminus binding PLEKHB1; PRKAA1; TFCP2; PIAS4; FBLN1; TERF2; TCF4; PXK; RABAC1; CD2AP
    protein binding RPUSD3; CHN2; NDUFB9; SKA1; PPFIA1; BET1; MCCC2; SLC6A18; INADL; PRKCQ
    protein complex binding SLC25A3; UQCRFS1; GNB4; CDK5RAP2; GRIN2A; MLC1; TELO2; CAV3; ATG101; PPFIA2
    protein phosphatase binding PPME1; PIK3R2; PPP1R3G; GNB2L1; Itga10&Itgb1; JAK1; STAT6; KCNN4; DLG3; LCK
    scaffold protein binding MAP2K2; PARK7; CACNA1G; SCN5A; ADCY6; VIM; NLGN1; DSP; CHRNA7; CIT

    DLG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG4.

    Kcna4; ERBB4; Dlgap1; KCNA4

    Dorostkar, MM; Burgold, S; et al. Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer's disease mouse model. BRAIN 137:3319-3326(2014).

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