Recombinant Human ERC1 Protein, MYC/DDK-tagged

• Cat.No.: ERC1-2115H
• Product Overview: Recombinant human ERC1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 127.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ERC1 ELKS/RAB6-interacting/CAST family member 1 [ Homo sapiens ]
• Official Symbol: ERC1
• Synonyms: Cast2; ELKS; ERC-1; RAB6IP2
• Gene ID: 23085
• mRNA Refseq: NM_178039
• Protein Refseq: NP_829883
• MIM: 607127
• UniProt ID: Q8IUD2