"FCGRT" Related Products

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Recombinant Human FCGRT/B2M protein, His/Strep II-tagged

Cat.No.: FCGRT & B2M-1925H
Product Overview: Recombinant Human FCGRT(Ala 24 - Ser 297)/B2M(Ile 21 - Met 119), subunit FCGRT / FcRN is fused with his-tag at the C-terminus and subunit Beta-2 microglobulin (B2M) is fused with Strep II-tag at the C-terminus was expressed in HEK293.
Source: HEK293
Species: Human
Tag: His/Strep II
Predicted N Terminal: Ala 24(FcRN) & Ile 21(B2M)
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: Has a calculated MW of 31.2 kDa (FCGRT / FcRN) and 13.1 kDa (B2M). DTT-reduced Protein migrates as 33 kDa (FCGRT) and 13 kDa (B2M) respectively due to glycosylation
Protein length: FCGRT(Ala 24 - Ser 297)/B2M(Ile 21 - Met 119)
Endotoxin: Less than 1.0 EU per μg of the Human FcRn / FCGRT & B2M by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Reconstitution: See Certificate of Analysis for reconstitution instructions and specific concentrations.
Gene Name: FCGRT Fc fragment of IgG, receptor, transporter, alpha [ Homo sapiens ]
Official Symbol: FCGRT
Synonyms: FCGRT; Fc fragment of IgG, receptor, transporter, alpha; IgG receptor FcRn large subunit p51; alpha chain; FCRN; FcRn alpha chain; neonatal Fc receptor; neonatal Fc-receptor for Ig; IgG Fc fragment receptor transporter alpha chain; immunoglobulin receptor, intestinal, heavy chain; major histocompatibility complex class I-like Fc receptor; alpha-chain;
Gene ID: 2217
mRNA Refseq: NM_001136019
Protein Refseq: NP_001129491
MIM: 601437
UniProt ID: P55899
Chromosome Location: 19q13.3
Function: IgG binding; beta-2-microglobulin binding; receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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