Recombinant Human FGG Protein, MYC/DDK-tagged

• Cat.No.: FGG-2239H
• Product Overview: Recombinant human FGG protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 46.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FGG fibrinogen gamma chain [ Homo sapiens ]
• Official Symbol: FGG
• Synonyms: fibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain
• Gene ID: 2266
• mRNA Refseq: NM_000509
• Protein Refseq: NP_000500
• MIM: 134850
• UniProt ID: P02679