Recombinant Human KLHL21 Protein (E2-H597), His/Strep tagged

• Cat.No.: KLHL21-1244H
• Product Overview: Recombinant Human 8His-StrepII-TEV-(GG)-KLHL21(E2-H597 end) Protein was expressed in Insect cell.

Specification

• Description: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
• Source: Insect cell
• Species: Human
• Tag: His/Strep
• Form: Liquid
• Protein Length: E2-H597
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: KLHL21 kelch-like 21 (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: KLHL21
• Synonyms: KLHL21; kelch-like 21 (Drosophila); kelch-like protein 21; KIAA0469; MGC99635
• Gene ID: 9903
• mRNA Refseq: NM_014851
• Protein Refseq: NP_055666
• UniProt ID: Q9UJP4