Recombinant Human LASP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LASP1-5401H
• Product Overview: LASP1 MS Standard C13 and N15-labeled recombinant protein (NP_006139) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.5 kDa
• AA Sequence: MNPNCARCGKIVYPTEKVNCLDKFW HKACFHCETCKMTLNMKNYKGYEKK PYCNAHYPKQSFTMVADTPENLRLK QQSELQSQVRYKEEFEKNKGKGFSV VADTPELQRIKKTQDQISNIKYHEE FEKSRMGPSGGEGMEPERRDSQDGS SYRRPLEQQQPHHIPTSAPVYQQPQ QQPVAQSYGGYKEPAAPVSIQRSAP GGGGKRYRAVYDYSAADEDEVSFQD GDTIVNVQQIDDGWMYGTVERTGDT GMLPANYVEAITRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LASP1 LIM and SH3 protein 1 [ Homo sapiens (human) ]
• Official Symbol: LASP1
• Synonyms: LASP1; LIM and SH3 protein 1; LIM and SH3 domain protein 1; Lasp 1; MLN50; MLN 50; metastatic lymph node gene 50 protein; Lasp-1
• Gene ID: 3927
• mRNA Refseq: NM_006148
• Protein Refseq: NP_006139
• MIM: 602920
• UniProt ID: Q14847