lasp1

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lasp1

Official Full Name LIM and SH3 protein 1
Background Lasp-1 is an actin-binding scaffolding protein that is overexpressed in 8-12% of breast cancers and is correlated to increased incidences of metastasis. Lasp-1 localizes to newly forming focal adhesions and membrane ruffles during cell migration (Lin, 2004).
Synonyms LASP1; LIM and SH3 protein 1; LIM and SH3 domain protein 1; Lasp 1; MLN50; MLN 50; metastatic lymph node gene 50 protein; Lasp-1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human LASP1-1206H Recombinant Human LASP1 Protein (1-243 aa), GST-tagged E.coli GST
    Human LASP1-1386H Recombinant Human LIM And SH3 Protein 1, His-tagged E.coli His
    Human LASP1-28501TH Recombinant Human LASP1 Wheat Germ N/A
    Human LASP1-4820HCL Recombinant Human LASP1 293 Cell Lysate HEK293 N/A
    Human LASP1-5401H Recombinant Human LASP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Lasp1-1296M Recombinant Mouse Lasp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat LASP1-3358R Recombinant Rat LASP1 Protein Mammalian Cell His
    Rhesus Macaque LASP1-2466R Recombinant Rhesus monkey LASP1 Protein, His-tagged Mammalian Cell His
    Chicken LASP1-4080C Recombinant Chicken LASP1 Mammalian Cell His
    Zebrafish LASP1-11914Z Recombinant Zebrafish LASP1 Mammalian Cell His

    lasp1 involved in several pathways and played different roles in them. We selected most pathways lasp1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with lasp1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    lasp1 has several biochemical functions, for example, SH3/SH2 adaptor activity, actin filament binding, ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by lasp1 itself. We selected most functions lasp1 had, and list some proteins which have the same functions with lasp1. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity ARHGAP4; STAM; CRKL; GRAP; NCK2; HSH2D; GRB7; LASP1; PAG1; BLNK
    actin filament binding PLDN; LIMA1; SVILA; MYO3A; SYNE1; TULP1; MARCKS; AJUBA; BLOC1S6; TMEM201
    ion transmembrane transporter activity GJA1; SFXN4; S100A6; SFXN5B; TRPV2; SFXN1; SFXN2; SFXN3; LASP1; SFXN5A
    protein binding ABHD1; SLC35A2; ALDOC; HIST1H2AM; POLD2; DYM; XIRP2; ZBTB44; REXO1L1; PPP6R2
    zinc ion binding MUL1B; UMPS; AICDA; PHF10; L3MBTL4; CA13; UBR4; GCH1; RXRGA; PRKCBB

    lasp1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lasp1 here. Most of them are supplied by our site. Hope this information will be useful for your research of lasp1.

    TRIP13; MDFI; TJP2; ARHGEF15

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