Recombinant Human LCP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LCP2-4623H
• Product Overview: LCP2 MS Standard C13 and N15-labeled recombinant protein (NP_005556) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 60.2 kDa
• AA Sequence: MALRNVPFRSEVLGWDPDSLADYFK KLNYKDCEKAVKKYHIDGARFLNLT ENDIQKFPKLRVPILSKLSQEINKN EERRSIFTRKPQVPRFPEETESHEE DNGGWSSFEEDDYESPNDDQDGEDD GDYESPNEEEEAPVEDDADYEPPPS NDEEALQNSILPAKPFPNSNSMYID RPPSGKTPQQPPVPPQRPMAALPPP PAGRNHSPLPPPQTNHEEPSRSRNH KTAKLPAPSIDRSTKPPLDRSLAPF DREPFTLGKKPPFSDKPSIPAGRSL GEHLPKIQKPPLPPTTERHERSSPL PGKKPPVPKHGWGPDRRENDEDDVH QRPLPQPALLPMSSNTFPSRSTKPS PMNPLPSSHMPGAFSESNSSFPQSA SLPPYFSQGPSNRPPIRAEGRNFPL PLPNKPRPPSPAEEENSLNEEWYVS YITRPEAEAALRKINQDGTFLVRDS SKKTTTNPYVLMVLYKDKVYNIQIR YQKESQVYLLGTGLRGKEDFLSVSD IIDYFRKMPLLLIDGKNRGSRYQCT LTHAAGYPTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LCP2 lymphocyte cytosolic protein 2 [ Homo sapiens (human) ]
• Official Symbol: LCP2
• Synonyms: LCP2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kD), SLP76; lymphocyte cytosolic protein 2; 76 kDa tyrosine phosphoprotein; SH2 domain containing leukocyte protein of 76kD; SLP 76; SLP-76 tyrosine phosphoprotein; SH2 domain-containing leukocyte protein of 76kD; SH2 domain-containing leukocyte protein of 76 kDa; SLP76; SLP-76
• Gene ID: 3937
• mRNA Refseq: NM_005565
• Protein Refseq: NP_005556
• MIM: 601603
• UniProt ID: Q13094