Recombinant Human LGI1 Protein (1-557), N-GST-tagged
| Cat.No. : | LGI1-10H |
| Product Overview : | Human LGI1 full-length ORF ( AAH22500, 1 a.a. - 557 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro). |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. |
| Source : | Wheat Germ |
| Species : | Human |
| Tag : | N-GST |
| Molecular Mass : | 86.79 kDa |
| Protein Length : | 1-557 |
| AA Sequence : | MESERSKRMGNACIPLKRIAYFLCL LSALLLTEGKKPAKPKCPAVCTCTK DNALCENARSIPRTVPPDVISLSFV RSGFTEISEGSFLFTPSLQLLLFTS NSFDVISDDAFIGLPHLEYLFIENN NIKSISRHTFRGLKSLIHLSLANNN LQTLPKDIFKGLDSLTNVDLRGNSF NCDCKLKWLVEWLGHTNATVEDIYC EGPPEYKKRKINSLSSKDFDCIITE FAKSQDLPYQSLSIDTFSYLNDEYV VIAQPFTGKCIFLEWDHVEKTFRNY DNITGTSTVVCKPIVIETQLYVIVA QLFGGSHIYKRDSFANKFIKIQDIE ILKIRKPNDIETFKIENNWYFVVAD SSKAGFTTIYKWNGNGFYSHQSLHA WYRDTDVEYLEIVRTPQTLRTPHLI LSSSSQRPVIYQWNKATQLFTNQTD IPNMEDVYAVKHFSVKGDVYICLTR FIGDSKVMKWGGSSFQDIQRMPSRG SMVFQPLQINNYQYAILGSDYSFTQ VYNWDAEKAKFVKFQELNVQAPRSF THVSINKRNFLFASSFKGNTQIYKH VIVDLSA |
| Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Gene Name : | LGI1 leucine rich glioma inactivated 1 [ Homo sapiens (human) ] |
| Official Symbol : | LGI1 |
| Synonyms : | LGI1; leucine rich glioma inactivated 1; EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN; leucine-rich glioma-inactivated protein 1; epitempin-1 |
| Gene ID : | 9211 |
| mRNA Refseq : | NM_005097 |
| Protein Refseq : | NP_005088 |
| MIM : | 604619 |
| UniProt ID : | O95970 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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