Recombinant Human LPL Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LPL-5717H
• Product Overview: LPL MS Standard C13 and N15-labeled recombinant protein (NP_000228) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 53.2 kDa
• AA Sequence: MESKALLVLTLAVWLQSLTASRGGV AAADQRRDFIDIESKFALRTPEDTA EDTCHLIPGVAESVATCHFNHSSKT FMVIHGWTVTGMYESWVPKLVAALY KREPDSNVIVVDWLSRAQEHYPVSA GYTKLVGQDVARFINWMEEEFNYPL DNVHLLGYSLGAHAAGIAGSLTNKK VNRITGLDPAGPNFEYAEAPSRLSP DDADFVDVLHTFTRGSPGRSIGIQK PVGHVDIYPNGGTFQPGCNIGEAIR VIAERGLGDVDQLVKCSHERSIHLF IDSLLNEENPSKAYRCSSKEAFEKG LCLSCRKNRCNNLGYEINKVRAKRS SKMYLKTRSQMPYKVFHYQVKIHFS GTESETHTNQAFEISLYGTVAESEN IPFTLPEVSTNKTYSFLIYTEVDIG ELLMLKLKWKSDSYFSWSDWWSSPG FAIQKIRVKAGETQKKVIFCSREKV SHLQKGKAPAVFVKCHDKSLNKKSG TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LPL lipoprotein lipase [ Homo sapiens (human) ]
• Official Symbol: LPL
• Synonyms: LPL; lipoprotein lipase; LIPD; HDLCQ11; lipoprotein lipase; phospholipase A1; EC 3.1.1.32; EC 3.1.1.34
• Gene ID: 4023
• mRNA Refseq: NM_000237
• Protein Refseq: NP_000228
• MIM: 609708
• UniProt ID: P06858