• Official Full Name

    Lipoprotein Lipase

  • Background

    LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
  • Synonyms

    LIPD; HDLCQ11; EC; LPL; lipoprotein lipase; MGC137861; OTTHUMP00000034806;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Assay Kits
    • Species :
    • Chicken
    • Chinese hamster
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • his
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • MYC
    • N/A
    • N
    Species Cat.# Product name Source (Host) Tag Price
    Human LPL-27722TH Recombinant Human LPL, FLAG-tagged HEK293 Flag
    Human LPL-1015H Recombinant Human LPL protein, Flag-tagged HEK293 Flag
    Human LPL-1014H Recombinant Human LPL, His-tagged E.coli his
    Human LPL-556H Recombinant Human LPL Protein, His-tagged E.coli His
    Human LPL-4665HCL Recombinant Human LPL 293 Cell Lysate HEK293 N/A
    Human LPL-4715H Recombinant Human LPL Protein, GST-tagged Wheat Germ GST
    Human LPL-5717H Recombinant Human LPL Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human LPL-2403H Recombinant Human LPL Protein, His-tagged E.coli N-His
    Human LPL-107HFL Recombinant Full Length Human LPL Protein, C-Flag-tagged Mammalian cells Flag
    Human LPL-22H  Active Recombinant Human LPL Protein, His-tagged CHO His
    Human LPL-5994HF Recombinant Full Length Human LPL Protein, GST-tagged In Vitro Cell Free System GST
    Human LPL-1312H Recombinant Human LPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Human LPL-1312H-B Recombinant Human LPL Protein Pre-coupled Magnetic Beads HEK293
    Mouse LPL-9205M Recombinant Mouse LPL Protein Mammalian Cell His
    Mouse LPL-379M Recombinant Mouse LPL protein, His-tagged Insect Cell His
    Mouse LPL-5143M Recombinant Mouse LPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Lpl-1335M Recombinant Mouse Lpl Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Lpl-1300M Recombinant Mouse Lpl protein, His&Myc-tagged HEK293 His&Myc
    Mouse LPL-5143M-B Recombinant Mouse LPL Protein Pre-coupled Magnetic Beads HEK293
    Mouse LPL-389M Recombinant Mouse LPL protein E.coli His
    Mouse LPL-388M Recombinant Mouse LPL protein, His & Myc-tagged E.coli His/Myc
    Mouse Lpl-3183M Recombinant Mouse Lpl protein E.coli N/A
    Rat LPL-3443R Recombinant Rat LPL Protein Mammalian Cell His
    Rat Lpl-557R Recombinant Rat Lpl Protein, His-tagged E.coli His
    Rat LPL-3099R-B Recombinant Rat LPL Protein Pre-coupled Magnetic Beads HEK293
    Rat LPL-3099R Recombinant Rat LPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Chinese hamster LPL-1389C Recombinant Chinese hamster LPL protein, His-tagged E.coli His
    Cynomolgus Monkey LPL-658C Recombinant Cynomolgus LPL Protein, His-tagged Mammalian Cell His
    Cynomolgus Monkey LPL-404C-B Recombinant Cynomolgus Monkey LPL Protein Pre-coupled Magnetic Beads HEK293
    Cynomolgus Monkey LPL-404C Recombinant Cynomolgus Monkey LPL Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Zebrafish LPL-8750Z Recombinant Zebrafish LPL Mammalian Cell His
    Chicken LPL-6834C Recombinant Chicken LPL Mammalian Cell His
    Kit-0521 Lipoprotein Lipase Activity Fluorometric Assay Kit N/A
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • LPL Related Articles
    • LPL Related Research Area

    LPL involved in several pathways and played different roles in them. We selected most pathways LPL participated on our site, such as Glycerolipid metabolism, PPAR signaling pathway, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with LPL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    LPL has several biochemical functions, for example, apolipoprotein binding, heparin binding, lipoprotein lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LPL itself. We selected most functions LPL had, and list some proteins which have the same functions with LPL. You can find most of the proteins on our site.

    Function Related Protein
    apolipoprotein bindingLPL;PCSK9;PLG;SCARB1;VLDLR;LRP6;LPA;CANX;LIPC
    heparin bindingLXN;CCL8;CTGF;VTN;LTBP2;ADAMTS1;PF4;FGF1;FGF1A
    lipoprotein lipase activityAOAH;LPL;LIPG
    phospholipase activityPLA2G10;ABHD6;DAGLB;LIPN;LIPH;LIPI;CEL.1;LIPG;Cel
    receptor bindingGLA;PGR;DAO1;ANGPTL2;PCSK1N;CD70;RSPO2;ADM;HSPA1A
    triglyceride bindingLPL;CETP
    triglyceride lipase activityPNLIPRP1;PNLIPRP2;LIPC;LIPF;CES1;CES3;CEL.1;Cel;PNLIPRP3

    LPL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LPL here. Most of them are supplied by our site. Hope this information will be useful for your research of LPL.


    Beigneux, AP; Fong, LG; et al. GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding. CIRCULATION RESEARCH 116:624-U152(2015).
    Toth-Liptak, J; Piukovics, K; et al. A Comprehensive Immunophenotypic Marker Analysis of Hairy Cell Leukemia in Paraffin-Embedded Bone Marrow Trephine Biopsies-A Tissue Microarray Study. PATHOLOGY & ONCOLOGY RESEARCH 21:203-211(2015).
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