Recombinant Human MTCH2 Protein, GST/His-tagged

• Cat.No.: MTCH2-2010H
• Product Overview: Recombinant human MTCH2 protein, fused to GST-tagged at N-terminus and His-tagged at C-terminus, was expressed in E. coli

Specification

• Description: This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon. [provided by RefSeq, Nov 2015].
• Source: E. coli
• Species: Human
• Tag: GST/His
• Form: 25 mM Tris, pH 8.0,150 mM NaCl,10% glycerol,1% Sarkosyl.
• Molecular Mass: 59.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MTCH2 mitochondrial carrier 2 [ Homo sapiens ]
• Official Symbol: MTCH2
• Synonyms: HSPC032; MIMP; SLC25A50
• Gene ID: 23788
• mRNA Refseq: NM_014342
• Protein Refseq: NP_055157
• MIM: 613221
• UniProt ID: Q9Y6C9