Recombinant Human PAFAH1B1 Protein, MYC/DDK-tagged

• Cat.No.: PAFAH1B1-201H
• Product Overview: Recombinant human PAFAH1B1 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Description: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 46.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: platelet activating factor acetylhydrolase 1b regulatory subunit 1 [ Homo sapiens ]
• Official Symbol: PAFAH1B1
• Synonyms: LIS1; LIS2; MDCR; MDS; NudF; PAFAH
• Gene ID: 5048
• Protein Refseq: NP_000421
• MIM: 601545