Description : |
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Form : |
Lyophilized |
Molecular Mass : |
28 kDa |
Protein Length : |
417 |
AA Sequence : |
MARAMAAAWPLLLVALLVLSWPPPG TGDVVVQAPTQVPGFLGDSVTLPCY LQVPNMEVTHVSQLTWARHGESGSM AVFHQTQGPSYSESKRLEFVAARLG AELRNASLRMFGLRVEDEGNYTCLF VTFPQGSRSVDIWLRVLAKPQNTAE VQKVQLTGEPVPMARCVSTGGRPPA QITWHSDLGGMPNTSQVPGFLSGTV TVTSLWILVPSSQVDGKNVTCKVEH ESFEKPQLLTVNLTVYYPPEVSISG YDNNWYLGQNEATLTCDARSNPEPT GYNWSTTMGPLPPFAVAQGAQLLIR PVDKPINTTLICNVTNALGARQAEL TVQVKEGPPSEHSGISRNAIIFLVL GILVFLILLGIGIYFYWSKCSREVL WHCHLCPSSTEHASASANGHVSYSA VSRENSSSQDPQTEGTR |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Concentration : |
1 mg/mL |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |