Recombinant Human PYHIN1 Protein (M1-P492), His/Strep tagged

• Cat.No.: PYHIN1-0630H
• Product Overview: Recombinant Human 6His-Strep II-TEV-PYHIN1(M1-P492 end)-Flag Protein was expressed in E. coli.

Specification

• Description: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
• Source: E. coli
• Species: Human
• Tag: His/Strep
• Form: Liquid
• Protein Length: M1-P492
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PYHIN1 pyrin and HIN domain family, member 1 [ Homo sapiens (human) ]
• Official Symbol: PYHIN1
• Synonyms: PYHIN1; pyrin and HIN domain family, member 1; pyrin and HIN domain-containing protein 1; IFIX; MGC23885; interferon-inducible protein X; RP11-520H16.1
• Gene ID: 149628
• mRNA Refseq: NM_152501
• Protein Refseq: NP_689714
• MIM: 612677
• UniProt ID: Q6K0P9