Recombinant Human Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1
Cat.No. : | SERPINE1-1848H |
Product Overview : | Recombinantactive human SERPINE1 labeledwith Alexa Fluor 488 by iodoacetamide substitution at the N-terminal cysteine. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SERPINE1-1848H |
Description : | SERPINE1 is aprotein that in humans is encoded by the SERPINE1 gene. SERPINE1 is a serineprotease inhibitor (serpin) that functionsas the principal inhibitor of tissue plasminogen activator (tPA) andurokinase (uPA), the activators of plasminogen and hence fibrinolysis (thephysiological breakdown of blood clots). It is a serine protease inhibitor(serpin) protein (SERPINE1). |
Source : | E. coli |
Species : | Human |
Molecular Weight : | 43 kDa |
Form : | Frozen liquid in0.05 M Sodium Phosphate Buffer + 0.1 M NaCl + 1 mM EDTA, pH 6.6. |
Purity : | > 95% by SDS-PAGEanalysis. |
Concentration : | 2.5 mg/ml |
Storage : | Store at-80°C. Protect from light. Stable for 3 years from delivery. Avoid repeated freeze-thawcycles. |
OfficialSymbol : | SERPINE1 |
Gene Name : | SERPINE1 serpin peptidaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1[ Homo sapiens ] |
Synonyms : | SERPINE1; serpinpeptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1),member 1; PAI;PAI1; PAI-1; PLANH1; plasminogen activator inhibitor 1; serpin E1; OTTHUMP00000211478;endothelial plasminogen activator inhibitor; serine (or cysteine) proteinaseinhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
Gene ID : | 5054 |
mRNA Refseq : | NM_000602 |
Protein Refseq : | NP_000593 |
MIM : | 173360 |
UniProt ID : | P05121 |
Chromosome Location : | 7q21.3-q22 |
Pathway : | Adipogenesis;BMAL1:CLOCK/NPAS2 Activates Gene Expression; Blood Clotting Cascade; Chagasdisease (American trypanosomiasis); Circadian Clock; Complement andCoagulation Cascades; Direct p53 effectors; Dissolution of Fibrin Clot; E2Ftranscription factor network; HIF-1-alpha transcription factor network;HIF-2-alpha transcription factor network; Hemostasis; Platelet activation;Platelet degranulation; Regulation of nuclear SMAD2/3 signaling; Response toelevated platelet cytosolic Ca2+; Selenium Pathway; Senescence and Autophagy;TGF Beta Signaling Pathway; p53 signaling pathway |
Function : | peptidase inhibitoractivity; protease binding; protein binding; contributes_to receptor binding;serine-type endopeptidase inhibitor activity |
Products Types
◆ Native Protein | ||
SERPINE1-5514R | Native Rabbit Serpin Peptidase Inhibitor, Clade E (nexin, plasminogen activator inhibitor type 1), Member 1 | +Inquiry |
SERPINE1-29522TH | Native Human SERPINE1 | +Inquiry |
◆ Lysates | ||
SERPINE1-2383HCL | Recombinant Human SERPINE1 cell lysate | +Inquiry |
SERPINE1-001RCL | Recombinant Rat SERPINE1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0782 | SERPINE1 (Human) Chromogenic Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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