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Recombinant Human TNC protein, His-tagged

Cat.No.: TNC-32H
Product Overview: Recombinant Human TNC(1888-2201 aa) fused with His tag was expressed in E. coli.
Description: Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Source: E. coli
Species: Human
Tag: His
AA Sequence: DSPRDLTATE VQSETALLTW RPPRASVTGY LLVYESVDGT VKEVIVGPDT TSYSLADLSP STHYTAKIQA LNGPLRSNMI QTIFTTIGLL YPFPKDCSQA MLNGDTTSGL YTIYLNGDKA EALEVFCDMT SDGGGWIVFL RRKNGRENFY QNWKAYAAGF GDRREEFWLG LDNLNKITAQ GQYELRVDLR DHGETAFAVY DKFSVGDAKT RYKLKVEGYS GTAGDSMAYH NGRSFSTFDK DTDSAITNCA LSYKG
Purity: Greater than 90% as determined by SDS-PAGE.
Storage: Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade.
Gene Name: TNC tenascin C [ Homo sapiens ]
Official Symbol: TNC
Synonyms: TNC; tenascin C; hexabrachion (tenascin C, cytotactin) , HXB; tenascin; hexabrachion (tenascin); MGC167029; TN; GP 150-225; cytotactin; neuronectin; myotendinous antigen; tenascin-C isoform 14/AD1/16; glioma-associated-extracellular matrix antigen; GP; JI; HXB; GMEM; TN-C; 150-225;
Gene ID: 3371
mRNA Refseq: NM_002160
Protein Refseq: NP_002151
MIM: 187380
UniProt ID: P24821
Chromosome Location: 9q32-q34
Pathway: ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Integrin cell surface interactions, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function: binding; receptor binding; syndecan binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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