TNC
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Official Full Name
tenascin C
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Overview
Tenascins are extracellular matrix glycoproteins. They are abundant in the extracellular matrix of developing vertebrate embryos and they reappear around healing wounds and in the stroma of some tumors. -
Synonyms
Tenascin-X; tenascin XB1; tenascin XB2; OTTHUMP00000174881; tenascin XB; OTTHUMP00000216549; hexabrachion-like protein; growth-inhibiting protein 45; XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; TNXBS; TNXB;
- Recombinant Proteins
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rabbit
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human glioma cell line (U251)
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
TNC involved in several pathways and played different roles in them. We selected most pathways TNC participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PIK-Akt signaling pathway | LAMA5;GNB2;IFNA13;VEGFA;Il4ra;PPP2R2C;MTCP1;THBS4;FOXO3 |
| Focal adhesion | ITGB5;ITGA10;TNR;COL6A4;PAK7;VTNB;PAK2;FYNA;KDR |
| ECM-receptor interaction | SV2B;GP5;COL3A1;FN1A;GP9;ITGB6;COL4A5;COL27A1B;VTNB |
| MicroRNAs in cancer | FOXP1;NOTCH2;PLCG1;FZD3;TTC6;EZH2;CCNE1;NOTCH4;CCNG1 |
TNC has several biochemical functions, for example, syndecan binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TNC itself. We selected most functions TNC had, and list some proteins which have the same functions with TNC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syndecan binding | SEMA5A;CHRD;SDCBP;TNC;HPSE |
TNC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNC here. Most of them are supplied by our site. Hope this information will be useful for your research of TNC.
Research Area
Related articles
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Customer Reviews (3)
Write a reviewUsing TNC, the lower limit of detection of Western blot was significantly reduced.
The repeatability of TNC is very good, which can reduce the error in the experiment and improve the reproducibility of the experiment.
TNC were labeled very well and could be used for fluorescent labeling, etc., which was very suitable for our study.
Q&As (6)
Ask a questionSome studies have found that TNC protein plays a role in cardiovascular diseases such as atherosclerosis, myocardial infarction, etc., and may participate in pathophysiological processes.
TNC protein plays an important role in the development and repair of the nervous system, including neuronal migration, axon growth and synapse formation.
Some studies have found that TNC protein is associated with neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, and may be involved in the occurrence and development of diseases.
TNC protein measurement can be used for cancer diagnosis and disease prognosis, but further studies are needed to confirm a direct link with TNC protein function.
TNC protein plays a role in immune regulation, can regulate inflammatory response, promote the activation and migration of immune cells, etc.
This protein plays an important role in tissue repair, can regulate cell migration, cell proliferation, and the formation of new blood vessels, and promote tissue repair.
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