Recombinant Human TRIP13 Protein (M1-I432), His/Strep tagged

• Cat.No.: TRIP13-0828H
• Product Overview: Recombinant Human 6His-StrepII-TEV-GG-TRIP13(M1-I432 end) Protein was expressed in E. coli.

Specification

• Description: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation.
• Source: E. coli
• Species: Human
• Tag: His/Strep
• Form: Liquid
• Protein Length: M1-I432
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: TRIP13 thyroid hormone receptor interactor 13 [ Homo sapiens (human) ]
• Official Symbol: TRIP13
• Synonyms: TRIP13; thyroid hormone receptor interactor 13; pachytene checkpoint protein 2 homolog; 16E1BP; thyroid receptor interacting protein 13; 16E1-BP; TRIP-13; TR-interacting protein 13; HPV16 E1 protein binding protein; HPV16 E1 protein-binding protein; thyroid receptor-interacting protein 13; human papillomavirus type 16 E1 protein-binding protein
• Gene ID: 9319
• mRNA Refseq: NM_001166260
• Protein Refseq: NP_001159732
• MIM: 604507
• UniProt ID: Q15645