Recombinant Mouse Cracr2a Protein, Myc/DDK-tagged
Cat.No. : | Cracr2a-2303M |
Product Overview : | Purified recombinant protein of mouse full-length calcium release activated channel regulator 2A (Cracr2a), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Ca2+-binding protein that plays a key role in store-operated Ca2+ entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+ resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 35.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cracr2a calcium release activated channel regulator 2A [ Mus musculus (house mouse) ] |
Official Symbol : | Cracr2a |
Synonyms : | Cracr2a; calcium release activated channel regulator 2A; Gm462; Efcab4; Gm1073; Efcab4b; EF-hand calcium-binding domain-containing protein 4B; EF-hand calcium binding domain 4B |
Gene ID : | 381812 |
mRNA Refseq : | NM_001033464 |
Protein Refseq : | NP_001028636 |
UniProt ID : | Q3UP38 |
Products Types
◆ Recombinant Protein | ||
CRACR2A-3083H | Recombinant Human CRACR2A Protein, GST-tagged | +Inquiry |
CRACR2A-3332H | Recombinant Human CRACR2A Protein, MYC/DDK-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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