Recombinant Mouse Naa80 Protein, Myc/DDK-tagged

• Cat.No.: Naa80-4271M
• Product Overview: Purified recombinant protein of mouse full-length N(alpha)-acetyltransferase 80, NatH catalytic subunit (Naa80), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively). N-terminal acetylation of processed beta- and gamma-actin regulates actin filament depolymerization and elongation. In vivo, preferentially displays N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu. In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp. May act as a tumor suppressor.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 34.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit [ Mus musculus (house mouse) ]
• Official Symbol: Naa80
• Synonyms: Naa80; N(alpha)-acetyltransferase 80, NatH catalytic subunit; Na; Fus2; Nat6; AI225910; N-alpha-acetyltransferase 80; N-acetyltransferase 6; protein fus-2; protein fusion-2 homolog; EC 2.3.1.-
• Gene ID: 56441
• mRNA Refseq: NM_019750
• Protein Refseq: NP_062724
• UniProt ID: Q9R123