Recombinant Mouse Ndufv1 Protein, Myc/DDK-tagged

• Cat.No.: Ndufv1-4348M
• Product Overview: Purified recombinant protein of mouse full-length NADH:ubiquinone oxidoreductase core subunit V1 (Ndufv1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes the transfer of electrons from NADH to the electron acceptor ubiquinone. The proton gradient created by electron transfer drives the conversion of ADP to ATP. This gene is a core subunit and is conserved in prokaryotes and eukaryotes. The human ortholog of this protein has been characterized. It has consensus motifs for NADH, flavin mononucleotide, and iron-sulfur binding sites and participates in the oxidation of NADH as part of the dehydrogenase module of complex I. In humans, deficiencies in complex I are associated with myopathies, encephalomyopathies, and neurodegenerative disorders.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 50.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 [ Mus musculus (house mouse) ]
• Official Symbol: Ndufv1
• Synonyms: NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; CI-51kD; 24 kDa (FP); complex I-51kD; NADH dehydrogenase flavoprotein 1; NADH-ubiquinone oxidoreductase 51 kDa subunit
• Gene ID: 17995
• mRNA Refseq: NM_133666
• Protein Refseq: NP_598427
• UniProt ID: Q91YT0