Recombinant Mouse Ppp4r3a Protein, Myc/DDK-tagged

• Cat.No.: Ppp4r3a-5085M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 4 regulatory subunit 3A (Ppp4r3a), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 93.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp4r3a protein phosphatase 4 regulatory subunit 3A [ Mus musculus (house mouse) ]
• Official Symbol: Ppp4r3a
• Synonyms: Ppp4r3a; protein phosphatase 4 regulatory subunit 3A; Smek; Smek1; BC064465; mKIAA2010; 1110034C04Rik; serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1, suppressor of mek1
• Gene ID: 68734
• mRNA Refseq: NM_211355
• Protein Refseq: NP_997594
• UniProt ID: Q6P2K6