Active Recombinant Mouse RANK L Protein
| Cat.No. : | RANK L-547M |
| Product Overview : | Recombinant Mouse RANK L Protein(NP_033425.3) was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
| Description : | Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a member of the TNF superfamily. RANKL also has a function in the immune system, where it is expressed by T helper cells and is thought to be involved in dendritic cell maturation. The murine TRANCE cDNA encodes a type II transmembrane protein of 316 amino acids with a predicted cytoplasmic domain of 48 amino acids and extracellular of 247 amino acids. Mouse and human TRANCE share 85% amino acid sequence identity. TRANCE is primarily expressed in T cells and T cell rich organs, such as thymus and lymph nodes. |
| Source : | E. coli |
| Species : | Mouse |
| Tag : | N/A |
| Predicted N Terminal : | Met |
| Bio-activity : | The ED50 for this effect is typically 0.5-2ng/ml |
| Endotoxin : | <0.01 EU/µg of the protein |
| Purity : | >95% by SDS-PAGE gel under reducing conditions and visualized by silver stain. |
| Reconstitution : | 400ng/µl in sterile PBS. |
| Gene Name : | Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator [ Mus musculus (house mouse) ] |
| Official Symbol : | Tnfrsf11a |
| Synonyms : | R; OFE; ODFR; Rank; TRAN; Ly109; mRANK; TRANCE-R |
| Gene ID : | 21934 |
| mRNA Refseq : | NM_009399.4 |
| Protein Refseq : | NP_033425.3 |
| UniProt ID : | O35305 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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