Active Recombinant Human OSCAR Protein, Fc-tagged
Cat.No. : | OSCAR-22H |
Product Overview : | Recombinant human OSCAR (Asp19-Asn229) protein fused with Fc region of human IgG1 (Pro100-Lys330) at C-terminus was expressed in mouse myeloma cell line. |
- Specification
- Gene Information
- Related Products
Description : | Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Fc |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Bovine Collagen I is coated at 10 µg/mL, Recombinant Human OSCAR Fc Chimera binds with an ED50 of 1-8 ng/mL. |
Molecular Mass : | 50 kDa |
N-terminal Sequence Analysis : | Asp19 |
Endotoxin : | <0.10 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | 12 months from date of receipt, ≤ -20 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Preservative : | Reconstitute at 500 μg/mL in PBS. |
Gene Name : | OSCAR osteoclast associated, immunoglobulin-like receptor [ Homo sapiens (human) ] |
Official Symbol : | OSCAR |
Synonyms : | hOSCAR; MGC33613; OSCAR; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIGR3; PIgR-3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3 |
Gene ID : | 126014 |
mRNA Refseq : | NM_133169 |
Protein Refseq : | NP_573399 |
MIM : | 606862 |
UniProt ID : | Q8IYS5 |
Products Types
◆ Recombinant Protein | ||
OSCAR-2829H | Recombinant Human OSCAR Protein, His-tagged, OVA Conjugated | +Inquiry |
OSCAR-6414M | Recombinant Mouse OSCAR Protein, His (Fc)-Avi-tagged | +Inquiry |
OSCAR-131H | Recombinant Human OSCAR Protein, His (Fc)-Avi-tagged | +Inquiry |
Oscar-001M | Active Recombinant Mouse Oscar Protein, Fc-tagged | +Inquiry |
Oscar-4614M | Recombinant Mouse Oscar Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
OSCAR-3528HCL | Recombinant Human OSCAR 293 Cell Lysate | +Inquiry |
OSCAR-3527HCL | Recombinant Human OSCAR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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