Active Recombinant Mouse Oscar Protein, Fc-tagged

• Cat.No.: Oscar-001M
• Product Overview: Recombinant mouse Oscar (Asp19-Asn228) protein fused with Fc region of human IgG1 (Pro100-Lys330) at C-terminus was expressed in mouse myeloma cell line.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: 19-228 a.a.
• Description: Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
• Form: Disulfide-linked homodimer
• Bio-activity: Measured by its binding ability in a functional ELISA. When Bovine Collagen I is coated at 10 µg/mL, Recombinant Mouse OSCAR Fc Chimera binds with an ED50 of 80-640 ng/mL.
• Molecular Mass: 49 kDa
• N-terminal Sequence Analysis: Asp19
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: 12 months from date of receipt, ≤ -20 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Preservative: Reconstitute at 500 μg/mL in PBS.

Gene Information

• Gene Name: Oscar osteoclast associated receptor [ Mus musculus (house mouse) ]
• Official Symbol: Oscar
• Synonyms: mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; Oscar; osteoclast associated receptor; osteoclast-associated immunoglobulin-like receptor; ocl178; osteoclast-associated receptor OSCAR
• Gene ID: 232790
• mRNA Refseq: NM_175632
• Protein Refseq: NP_783440
• UniProt ID: Q8VBT3