"NUDT3" Related Products

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Recombinant Human NUDT3, His-tagged

Cat. No.: NUDT3-3476H
Product Overview: Recombinant human NUDT3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: NUDT3, also known as DIPP, DIPP1 (diphosphoinositol polyphosphate phosphohydrolase 1), is a 172 amino acid cytoplasmic protein belonging to the nudix hydrolase family and DIPP subfamily. NUDT3 acts as a negative regulator of the ERK 1/2 pathway and hydrolyzes 5-phosphoribose 1-diphosphate. NUDT3 exists as a monomer and binds magnesium as a cofactor. Also NUDT3 is widely expressed but found at highest levels in liver, pancreas, brain and heart.
Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol
Molecular Weight: 21.6 kDa (192aa) confirmed by MALDI-TOF
Purity: > 95% by SDS - PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MMKLKSNQTR TYDGDGYKKR AACLCFRSES EEEVLLVSSS RHPDRWIVPG GGMEPEEEPS VAAVREVCEE AGVKGTLGRL VGIFENQERK HRTYVYVLIV TEVLEDWEDS VNIGRKREWF KIEDAIKVLQ YHKPVQASYF ETLRQGYSAN NGTPVVATTY SVSAQSSMSG IR
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 [ Homo sapiens ]
Synonyms: nudix (nucleoside diphosphate linked moiety X)-type motif 3; DIPP; DIPP1; NUDT3; diphosphoinositol polyphosphate phosphohydrolase 1; DIPP-1; nudix motif 3; nucleoside diphosphate-linked moiety X motif 3; diadenosine 5",5""-P1,P6-hexaphosphate hydrolase 1; NP_006694.1; EC 3.6.1.52
Gene ID: 11165
mRNA Refseq: NM_006703
Protein Refseq: NP_006694
MIM: 609228
UniProt ID: O95989
Chromosome Location: 6p21.2
Function: diphosphoinositol-polyphosphate diphosphatase activity; hydrolase activity; magnesium ion binding

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