NUDT21

  • Official Full Name

    nudix (nucleoside diphosphate linked moiety X)-type motif 21

  • Overview

    The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.

  • Synonyms

    NUDT21;nudix (nucleoside diphosphate linked moiety X)-type motif 21;cleavage and polyadenylation specific factor 5, 25 kD subunit , cleavage and polyadenylation specific factor 5, 25 kDa , CPSF5;cleavage and polyadenylation specificity factor subunit

Recombinant Proteins

  • Mouse
  • Human
  • Chicken
  • Mammalian Cells
  • Wheat Germ
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NUDT21-10972M Recombinant Mouse NUDT21 Protein Mammalian Cells Mouse His
NUDT21-1816H Recombinant Human NUDT21 Protein, GST-tagged Wheat Germ Human GST
NUDT21-27532TH Recombinant Human NUDT21, His-tagged E.coli Human His 227 amino acids
NUDT21-5051C Recombinant Chicken NUDT21 Mammalian Cells Chicken His
NUDT21-960H Recombinant Human NUDT21, His-tagged E.coli Human His
NUDT21-3646HCL Recombinant Human NUDT21 293 Cell Lysate HEK293 Human Non
NUDT21-2211HF Recombinant Full Length Human NUDT21 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 227 amino acids
Nudt21-4540M Recombinant Mouse Nudt21 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
NUDT21-5940H Recombinant Human NUDT21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NUDT21-6256M Recombinant Mouse NUDT21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NUDT21-6256M-B Recombinant Mouse NUDT21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NUDT21 involved in several pathways and played different roles in them. We selected most pathways NUDT21 participated on our site, such as Cleavage of Growing Transcript in the Termination Region,Gene Expression,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Processing of Capped Intron-Containing Pre-mRNA METTL3,BCAS2,METTL14,SFRS3A,SF3A1,CLP1,PTBP1B,SF3A3,PTBP1,CD2BP2
    RNA Polymerase II Transcription CCNT2B,CSTF3,CSTF2,THOC4,ZNF473,SRSF11,SUPT16H,RNPS1,SSRP1A,NELFE
    Processing of Capped Intronless Pre-mRNA PAPOLA,ZNF473,LSM11,ZFP473,CSTF3,CSTF1,CLP1,CSTF2,LSM10,SLBP
    Cleavage of Growing Transcript in the Termination Region LSM11,RNPS1,PAPOLA,CSTF1,ZNF473,SRSF11,SLBP,ZFP473,U2AF2,CSTF3
    RNA Polymerase II Transcription Termination THOC4,CSTF1,PAPOLA,LSM11,LSM10,CLP1,RNPS1,SRSF11,ZFP473,CSTF3
    Processing of Intronless Pre-mRNAs PAPOLA,CSTF1,CSTF2,CLP1,CSTF3
    Gene Expression TRIM33,MED8,COX6A1,ZNF562,NR6A1A,EEF1E1,PIWIL4,PCBP2,ZFP37,ZNF45
    mRNA 3-end processing SRSF11,CLP1,CSTF2,SFRS3A,CSTF3

    Protein Function

    NUDT21 has several biochemical functions, for example, AU-rich element binding,contributes_to RNA binding,histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT21 itself. We selected most functions NUDT21 had, and list some proteins which have the same functions with NUDT21. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to RNA binding CPSF6,SMX5,LSM7
    hydrolase activity NCEH1A,ZRANB1B,GDPD4,TMPRSS13A,PPM1BA,FAHD2A,Atp8a2,ABHD2A,FAM49BA,ATP6V0E2
    protein binding SEPT2,CDC73,MYO9B,NFIX,SSX5,C16orf59,MAPK11,PLP2,JOSD1,UNC45A
    mRNA binding SNRNP35,PIWIL2,MECP2,SOSTDC1B,QK,NXF2,ITM2B,EIF4A3,CROP,CCDC55
    poly(A) RNA binding PRPF4B,CCDC59,RPS17L,RPL10,SRSF4,SF3A2,PELP1,HSD17B10,ANP32A,UTP11L
    histone deacetylase binding RELA,SIX3,TOP2A,MEF2A,HIC1,HES1,XBP1,PARK2,CRY1,YY1
    protein homodimerization activity TERF1,CADM4,SDS,CRYBA2,BMP4,PTPRE,KLHL7,RABEP1,NOG,TNNC1
    AU-rich element binding ZFP36L3,EXOSC8,ELAVL4,ELAVL1,ZFP36L1,TIA1,APOBEC1,CPSF5,TIAL1,ZFP36

    Interacting Protein

    NUDT21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT21 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT21.

    CPSF7;CPSF6;TRIM27;GOLGA2;RNPS1

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