NUDT21

  • Official Full Name

    nudix (nucleoside diphosphate linked moiety X)-type motif 21

  • Overview

    The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.

  • Synonyms

    NUDT21;nudix (nucleoside diphosphate linked moiety X)-type motif 21;cleavage and polyadenylation specific factor 5, 25 kD subunit , cleavage and polyadenylation specific factor 5, 25 kDa , CPSF5;cleavage and polyadenylation specificity factor subunit

Recombinant Proteins

  • Mouse
  • Chicken
  • Human
  • Mammalian Cells
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • GST
  • DDK
  • Myc
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NUDT21-10972M Recombinant Mouse NUDT21 Protein Mammalian Cells Mouse His
NUDT21-5051C Recombinant Chicken NUDT21 Mammalian Cells Chicken His
NUDT21-960H Recombinant Human NUDT21, His-tagged E.coli Human His
NUDT21-3646HCL Recombinant Human NUDT21 293 Cell Lysate HEK293 Human Non
NUDT21-2211HF Recombinant Full Length Human NUDT21 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 227 amino acids
Nudt21-4540M Recombinant Mouse Nudt21 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
NUDT21-5940H Recombinant Human NUDT21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NUDT21-6256M Recombinant Mouse NUDT21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NUDT21-6256M-B Recombinant Mouse NUDT21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NUDT21 involved in several pathways and played different roles in them. We selected most pathways NUDT21 participated on our site, such as Cleavage of Growing Transcript in the Termination Region,Gene Expression,Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA Polymerase II Transcription Termination PAPOLA,CLP1,LSM10,CSTF3,CSTF2,RNPS1,CSTF1,U2AF2,ZNF473,SLBP
    Gene Expression EIF2S1A,MTERF,ZNF688,NR2F6B,NFIC,SCO1,EIF1AX,MTA2,ZNF287,RPP30
    Cleavage of Growing Transcript in the Termination Region PAPOLA,ZFP473,THOC4,CSTF2,U2AF2,CSTF3,SRSF11,LSM11,ZNF473,CSTF1
    RNA Polymerase II Transcription RNPS1,LSM10,CCNT2A,CCNT2B,CSTF2,CLP1,ZFP473,SUPT16H,CSTF1,SSRP1A
    mRNA 3-end processing CSTF3,CSTF2,SFRS3A,SRSF11,CLP1
    Processing of Intronless Pre-mRNAs CSTF2,CSTF3,CLP1,PAPOLA,CSTF1
    Processing of Capped Intron-Containing Pre-mRNA BCAS2,CCAR1,PDCD7,PRPF8,RBM5,SF3B2,SF3B4,HNRNPA0A,PTBP1,HNRNPR
    Processing of Capped Intronless Pre-mRNA SLBP,CSTF2,LSM10,CSTF1,ZFP473,CSTF3,PAPOLA,CLP1,LSM11,ZNF473

    Protein Function

    NUDT21 has several biochemical functions, for example, AU-rich element binding,contributes_to RNA binding,histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT21 itself. We selected most functions NUDT21 had, and list some proteins which have the same functions with NUDT21. You can find most of the proteins on our site.

    Function Related Protein
    AU-rich element binding EXOSC4,HNRNPA0,DND1,CPSF5,ZFP36L1,TIA1,APOBEC1,ELAVL3,ZFP36,EXOSC7
    protein binding CLTB,KRT17,TFCP2,FTL,CARD9,TUBGCP3,NCSTN,HSPB9,CDC7,ZBTB1
    protein homodimerization activity SP1,CHKA,CLIC6,Flt3l,TLR13,TPD52L2,RAB11FIP2,TFRC,ADAM10,CHMP3
    hydrolase activity ATP2B1,MEST,NT5DC3,MMP25,Reln,CDC14A,PROCA,ABHD14A,ATP2A2B,CAPN2A
    poly(A) RNA binding MRPL41,MRPS21,UBFD1,YWHAZ,GTPBP1,RPSA,PRR3,BST2,LRP1,ACAA2
    histone deacetylase binding YY1,CEBPB,SFPQ,HEY2,HDAC4,PKN1,HES1,TFAP4,NKX3,RELA
    mRNA binding PIWIL2,PCBP1,RBPMS2B,LIN28A,PAIP2,LUC7L3,RBM25,PIWIL1,TDRD7,XPO5
    contributes_to RNA binding LSM7,SMX5,CPSF6

    Interacting Protein

    NUDT21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT21 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT21.

    CPSF7;CPSF6;TRIM27;GOLGA2;RNPS1

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