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Recombinant Human ACP1

Cat. No.: ACP1-1068H
Product Overview: Human ACP1 (NP_009030, 1 a.a.-158 a.a.) full-length recombinant protein with His tag expressed in Escherichia coli.
Description: The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes.
Sequence: MGSSHHHHHH SSGLVPRGSH MAEQATKSVL FVCLGNICRS PIAEAVFRKL VTDQNISENW VIDSGAVSDW NVGRSPDPRA VSCLRNHGIH TAHKARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKTC KAKIELLGSY DPQKQLIIED PYYGNDSDFE TVYQQCVRCC RAFLEKAH
Theoretical MW (kDa): 20.1
Form: Liquid
Preparation Method: E. coli expression system
Purity: > 95% by SDS-PAGE
Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
Activity: Activity tested: > 60,000 unit/mg of protein
Application: SDS-PAGE
Storage Buffer: In 20 mM MES 6.0, 0.1 mM PMSF, 2 mM EDTA (10% glycerol)
Storage: Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
Unitprot ID: P24666
Gene Name: ACP1 acid phosphatase 1, soluble [ Homo sapiens ]
Official Symbol: ACP1
Synonyms: HAAP; MGC3499; MGC111030; low molecular weight phosphotyrosine protein phosphatase; LMW-PTP; LMW-PTPase; OTTHUMP00000109538; OTTHUMP00000109539; OTTHUMP00000199909; OTTHUMP00000199910; OTTHUMP00000199911; OTTHUMP00000199914; adipocyte acid phosphatase; red cell acid phosphatase 1; protein tyrosine phosphatase; acid phosphatase of erythrocyte; cytoplasmic phosphotyrosyl protein phosphatase; low molecular weight cytosolic acid phosphatase
Gene ID: 52
mRNA Refseq: NM_007099
Protein Refseq: NP_009030
MIM: 171500
Chromosome Location: 2p25
Pathway: Adherens junction; adherens junction; EPHA2 forward signaling; PDGFR-beta signaling pathway; riboflavin metabolism; riboflavin metabolism
Function: Acid phosphatase activity; hydrolase activity; identical protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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