Recombinant Human Tyrosinase, GST-tagged
Cat.No. : | TYR-220H |
Product Overview : | Recombinant Human TYR (1 a.a. - 377 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ. |
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- Gene Information
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Cat. No. : | TYR-220H |
Description : | The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3'' half of this gene. |
Source : | wheat germ |
Molecular Mass : | 67.21 kDa |
Sequence : | MLLAVLYCLLWSFQTSAGHFPRACV SSKNLMEKECCPPWSGDRSPCGQLS GRGSCQNILLSNAPLGPQFPFTGVD DRESWPSVFYNRTCQCSGNFMGFNC GNCKFGFWGPNCTERRLLVRRNIFD LSAPEKDKFFAYLTLAKHTISSDYV IPIGTYGQMKNGSTPMFNDINIYDL FVWMHYYVSMDALLGGSEIWRDIDF AHEAPAFLPWHRLFLLRWEQEIQKL TGDENFTIPYWDWRDAEKCDICTDE YMGGQHPTNPNLLSPASFFSSWQIV CSRLEEYNSHQPLCNGTPEGPLRRN PGNHDKSRTPRLPSSADVEFCLSLT QYESGSMDKAANFSFRNTLEEMGFL HVGWAGLKLLTSRDPPPWPPKMLGL QA |
Storagebuffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
Applications : | ELISA; WB |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
OfficialSymbol : | TYR |
Gene Name : | TYR tyrosinase [ Homo sapiens (human) ] |
Synonyms : | TYR; tyrosinase; CMM8; OCA1A; OCAIA; SHEP3; LB24-AB; SK29-AB; monophenol monooxygenase; oculocutaneous albinism IA; tumor rejection antigen AB |
Gene ID : | 7299 |
mRNA Refseq : | NM_000372 |
Protein Refseq : | NP_000363 |
MIM : | 606933 |
UniProt ID : | P14679 |
Chromosome Location : | 11q14-q21 |
Pathway : | (S)-reticuline biosynthesis II; L-dopachrome biosynthesis; Melanogenesis; Tyrosine metabolism |
Function : | copper ion binding; metal ion binding; monooxygenase activity; protein binding; protein heterodimerization activity |
Products Types
◆ Recombinant Protein | ||
Tyr-6757M | Recombinant Mouse Tyr Protein, Myc/DDK-tagged | +Inquiry |
Tyr-518R | Recombinant Rat Tyr Protein, His-tagged | +Inquiry |
TYR-2965H | Recombinant Human TYR Protein, MYC/DDK-tagged | +Inquiry |
TYR-2286H | Recombinant Human TYR Protein, His (Fc)-Avi-tagged | +Inquiry |
TYR-2655H | Recombinant Human TYR protein(281-360 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
TYR-1869HCL | Recombinant Human TYR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0836 | Tyrosine Colorimetric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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