Recombinant Mouse Tyr Protein, Myc/DDK-tagged

• Cat.No.: Tyr-6757M
• Product Overview: Purified recombinant protein of mouse full-length tyrosinase (Tyr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
• Molecular Mass: 61.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tyr tyrosinase [ Mus musculus (house mouse) ]
• Official Symbol: Tyr
• Synonyms: TYR; tyrosinase; albino locus protein; monophenol monooxygenase; c; skc35; albino
• Gene ID: 22173
• mRNA Refseq: NM_011661
• Protein Refseq: NP_035791
• UniProt ID: P11344