Recombinant human SEC61B, His-tagged
Cat.No. : | SEC61B-2454H |
Product Overview : | Recombinant human SEC61B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT |
Molecular Mass : | 9.4kDa (93aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMPGPTPS GTNVGSSGRS PSKAVAARAA GSTVRQRKNA SCGTRSAGRT TSAGTGGMWR FYTEDSPGLKVGP |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.25mg/ml (determined by Bradford assay) |
Gene Name : | SEC61B Sec61 beta subunit [ Homo sapiens ] |
Official Symbol : | SEC61B |
Synonyms : | SEC61B; Sec61 beta subunit; protein transport protein Sec61 subunit beta; Sec61 complex, beta subunit; protein translocation complex beta; protein transport protein SEC61 beta subunit; |
Gene ID : | 10952 |
mRNA Refseq : | NM_006808 |
Protein Refseq : | NP_006799 |
MIM : | 609214 |
UniProt ID : | P60468 |
Chromosome Location : | 9q22.32-q31.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; ER-Phagosome pathway, organism-specific biosystem; Gene Expression, organism-specific biosystem; Immune System, organism-specific biosystem; |
Function : | epidermal growth factor binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
SEC61B-3945R | Recombinant Rhesus Macaque SEC61B Protein, His (Fc)-Avi-tagged | +Inquiry |
SEC61B-4128R | Recombinant Rhesus monkey SEC61B Protein, His-tagged | +Inquiry |
SEC61B-2567H | Recombinant Human SEC61B, His-tagged | +Inquiry |
SEC61B-5636C | Recombinant Chicken SEC61B | +Inquiry |
SEC61B-651Z | Recombinant Zebrafish SEC61B | +Inquiry |
◆ Lysates | ||
SEC61B-1578HCL | Recombinant Human SEC61B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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