SEC24A

  • Official Full Name

    SEC24 family, member A
  • Overview

    Coat Protein Complex II (COPII) is composed of five cytosolic proteins: Sec23/24 complex, Sec13/31 complex, and Sar1. COPII coat is located at the ER/Golgi interface and is involved in transport of newly synthesized proteins from the ER to the Golgi appar
  • Synonyms

    SEC24A;SEC24 family, member A (S. cerevisiae);SEC24 (S. cerevisiae) related gene family, member A;protein transport protein Sec24A;SEC24-related protein A;SEC24 related gene family, member A
Cat.# Product name Source (Host) Species Tag Protein Length Price
SEC24A-2565H Recombinant Human SEC24A, His-tagged E.coli Human His 264-613aa
SEC24A-14832M Recombinant Mouse SEC24A Protein Mammalian Cells Mouse His
SEC24A-46H Recombinant Human SEC24A protein, GST-tagged Wheat Germ Human GST 301-390 a.a.
SEC24A-7988M Recombinant Mouse SEC24A Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SEC24A-7988M-B Recombinant Mouse SEC24A Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SEC24A involved in several pathways and played different roles in them. We selected most pathways SEC24A participated on our site, such as Adaptive Immune System,Antigen Presentation: Folding, assembly and peptide loading of class I MHC,Asparagine N-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC24A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System KIF5B,CD207,TRIM29,CRCP,DTX3L,TREM1,CD180,CFHL3,CLEC2H,TAX1BP1
    COPII (Coat Protein 2) Mediated Vesicle Transport GORASP1,PPP6R1,PPP6C,TMED2,TRAPPC6A,TRAPPC3,SEC23IP,NSFA,TRAPPC9,SCFD1
    Cargo concentration in the ER CTSZ,CNIH3,TMED10,MCFD2,LMAN2,CNIH,SERPINA1L,CTAGE5,AREG,CNIH2
    presentation SPSB2,UBE2J2,DZIP3,RNF25,UBE2V1,CD207,FBXO17,ERAP1,CTSL2,RNF220
    Antigen Presentation: Folding, assembly and peptide loading of class I MHC SEC23A,B2ML,ERAP1,ERAP2
    Asparagine N-linked glycosylation MIA3,TFG,MGAT4A,MAN1B1,PPP6R3,SEC16B,ST3GAL3A,NAPG,SEC23IP,PPP6R1
    ER to Golgi Anterograde Transport NAPAB,TRAPPC2L,CNIH2,TRAPPC9,TRAPPC6BL,SEC22C,CTSC,SEC22A,TRAPPC6B,CTAGE5
    Class I MHC mediated antigen processing &amp ASB13,LRSAM1,UBE2E3,UBE2V2,RNF138,PJA2,UBR1,FCGR1B,ASB18,UBR2
    Adaptive Immune System OSBPL1A,ACTR1B,SRMS,SIGLEC5,KIF4,CD300E,SIGLEC11,TRIM9,CREB1B,SEC61B

    Protein Function

    SEC24A has several biochemical functions, for example, molecular_function,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC24A itself. We selected most functions SEC24A had, and list some proteins which have the same functions with SEC24A. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function FAM199X,WFDC15A,LIPK,PACRGL,CCDC129,TPRG,ZNF296,STRUMPELLIN,TMEM28,FNDC3C1
    protein binding OSTA,NUDCD2,ADAMTSL5,FAM9A,CLDN16,FAM113A,PIPOX,BCL2L13,KLB,SCYL2
    zinc ion binding ING5A,SLC30A8,TRIM58,USP49,TRAF4,S100A7,DNAJC21,SEC23B,NR3C2,ADAM5P

    Interacting Protein

    SEC24A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC24A here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC24A.

    EWSR1;TFG;TMED2;CBFA2T3;TRIP13;SEC16A;GABARAP;GABARAPL1;GTSE1

    Resources

    References

    • de Barsy, M; Mirabella, A; et al. A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells. MICROBIOLOGY-SGM 158:2610-2618(2012).

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