SEC24A
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Official Full Name
SEC24 family, member A -
Overview
Coat Protein Complex II (COPII) is composed of five cytosolic proteins: Sec23/24 complex, Sec13/31 complex, and Sar1. COPII coat is located at the ER/Golgi interface and is involved in transport of newly synthesized proteins from the ER to the Golgi appar -
Synonyms
SEC24A;SEC24 family, member A (S. cerevisiae);SEC24 (S. cerevisiae) related gene family, member A;protein transport protein Sec24A;SEC24-related protein A;SEC24 related gene family, member A
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEC24A-2565H | Recombinant Human SEC24A, His-tagged | E.coli | Human | His | 264-613aa | |
| SEC24A-14832M | Recombinant Mouse SEC24A Protein | Mammalian Cells | Mouse | His |
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| SEC24A-46H | Recombinant Human SEC24A protein, GST-tagged | Wheat Germ | Human | GST | 301-390 a.a. |
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| SEC24A-7988M | Recombinant Mouse SEC24A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| SEC24A-7988M-B | Recombinant Mouse SEC24A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SEC24A involved in several pathways and played different roles in them. We selected most pathways SEC24A participated on our site, such as Adaptive Immune System,Antigen Presentation: Folding, assembly and peptide loading of class I MHC,Asparagine N-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC24A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | SEC23A,ERAP2,B2ML,ERAP1 |
| presentation | VPRBP,SPSB2,RNF220,STUB1,BLMH,TRIM69,UBE2L6,ERAP1,FBXO3,ASB11 |
| Adaptive Immune System | CTSO,LILRA1,RBCK1,RAET1E,CD96,TRIM50,IGKV1-5,SLAMF6,STUB1,MAPKAP1 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | PPP6C,TRAPPC3,TRAPPC2L,LMAN2L,PREB,YKT6,TRAPPC6B,SEC22A,NAPAB,LMAN2 |
| Asparagine N-linked glycosylation | SEC22A,NAPAB,SEC22C,NAPAA,TRAPPC4,CTSC,BET1,TRAPPC6BL,LMAN2,ZNF408 |
| ER to Golgi Anterograde Transport | GOLGA2,MIA3,AREG,CNIH2,TMED2,USO1,LMAN2L,TRAPPC1,TRAPPC4,PREB |
| Immune System | CD160,TRIM50,IFIT8,NLRP4,MGC174857,TLR6,FBXO27,WASF3,IFI6,BTR29 |
| Cargo concentration in the ER | PREB,MIA3,AREG,SEC23A,LMAN2L,TMED2,CTSZ,SERPINA1L,TMED10,CNIH3 |
| Class I MHC mediated antigen processing & | UBE2E3,RNF19B,ASB13,FBXO3,ASB4,SPSB4,RNF6,TRIM39,TPP2,RNF182 |
Protein Function
SEC24A has several biochemical functions, for example, molecular_function,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC24A itself. We selected most functions SEC24A had, and list some proteins which have the same functions with SEC24A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | EP300,ING2,LIMS1,RC3H1,ARHGEF2,ESR2B,TAF3,ZCCHC16,TRIM16,ING5B |
| protein binding | GABBR1,AAGAB,GEMIN8,TSPAN2,SVIP,SNRPD3,GLYR1,SLAMF6,ADRM1,FAM131C |
| molecular_function | PHYHIPLB,SLAIN1B,SKINT3,IGSF21A,CPNE9,CDH3,SPATA2,FIP1L1B,GTSE1,TMCC2 |
Interacting Protein
SEC24A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC24A here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC24A.
EWSR1;TFG;TMED2;CBFA2T3;TRIP13;SEC16A;GABARAP;GABARAPL1;GTSE1
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References
- de Barsy, M; Mirabella, A; et al. A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells. MICROBIOLOGY-SGM 158:2610-2618(2012).
