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Official Full Name SEC23 interacting protein
Background This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene.
Synonyms SEC23IP; SEC23 interacting protein; SEC23-interacting protein; P125; MSTP053; Phospholipase; Sec23 interacting protein p125; OTTHUMP00000020613; P125A
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SEC23IP-1992HCL Recombinant Human SEC23IP 293 Cell Lysate HEK293 N/A
    Human SEC23IP-2564H Recombinant Human SEC23IP, GST-tagged E.coli GST
    Mouse Sec23ip-5746M Recombinant Mouse Sec23ip Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Zebrafish SEC23IP-4711Z Recombinant Zebrafish SEC23IP Mammalian Cell His

    sec23ip involved in several pathways and played different roles in them. We selected most pathways sec23ip participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with sec23ip were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Asparagine N-linked glycosylation PPP6R3; TRAPPC10; ST8SIA2; MIA3; NAPAA; NSFB; TRAPPC6A; MPDU1; ALG10B; GORASP1
    COPII (Coat Protein 2) Mediated Vesicle Transport LMAN2; TRAPPC1; NAPAB; NSFB; TRAPPC2L; CNIH; TFG; TRAPPC6BL; CNIH2; SERPINA1L
    ER to Golgi Anterograde Transport AREG; TRAPPC6BL; TRAPPC10; ANKRD28; TRAPPC2; CNIH; TRAPPC2L; SEC22A; SEC16B; CTAGE5
    Membrane Trafficking RALAA; HIP1R; COPZ1; PUM1; CX30.3; SCFD1; MYO1C; MYO6B; EXOC5; STXBP3
    Metabolism of proteins SPON1B; CPA3; MPDU1A; CTSH; STT3A; EXOC6; LDHD; CPE; DPAGT1; SEC61B
    Post-translational protein modification SENP5; TRAPPC6BL; MUC4; PHC1; SLC35A1; MUC13; MUC12; TRAPPC6A; ARSE; MAGT1
    Transport to the Golgi and subsequent modification PPP6C; PPP6R1; SEC23IP; LMAN2L; TRAPPC6B; NAPB; TRAPPC9; NAPG; SEC16B; TRAPPC3
    Vesicle-mediated transport GJA8; STXBP3; RAB10; SH3D19; TGOLN2; COPB2; CD163; DNASE2; RALAA; TBC1D8B

    sec23ip has several biochemical functions, for example, metal ion binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by sec23ip itself. We selected most functions sec23ip had, and list some proteins which have the same functions with sec23ip. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding ZBTB22; ATP11A; LNX2B; DMRT2; ZFP746; CYP2D10; ALKBH5; ZFR; PPARG; UQCRC2A
    poly(A) RNA binding SBDS; HNRNPD; ANXA2; TRA2B; BUD13; RPS17L; DHX15; RPL26L1; KRR1; PES1
    protein binding SGOL1; FAM113A; PTPRD; CRCP; OTUB1; CBFA2T3; MRM1; CBR2; GNAS; SRSF7

    sec23ip has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sec23ip here. Most of them are supplied by our site. Hope this information will be useful for your research of sec23ip.

    SSC5D; HSPB11; PDCD6; Sec24c; Kif4; PRKD2; Vps28; TIMM13

    de Barsy, M; Mirabella, A; et al. A Brucella abortus cstA mutant is defective for association with endoplasmic reticulum exit sites and displays altered trafficking in HeLa cells. MICROBIOLOGY-SGM 158:2610-2618(2012).

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