Recombinant Human MLKL, GST-tagged

• Cat.No.: MLKL-95H
• Product Overview: Recombinant Human MLKL(1 a.a. - 471 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.9 kDa
• AA Sequence: MENLKHIITLGQVIHKRCEEMKYCK KQCRRLGHRVLGLIKPLEMLQDQGK RSVPSEKLTTAMNRFKAALEEANGE IEKFSNRSNICRFLTASQDKILFKD VNRKLSDVWKELSLLLQVEQRMPVS PISQGASWAQEDQQDADEDRRAFQM LRRDNEKIEASLRRLEINMKEIKET LRQYLPPKCMQEIPQEQIKEIKKEQ LSGSPWILLRENEVSTLYKGEYHRA PVAIKVFKKLQAGSIAIVRQTFNKE IKTMKKFESPNILRIFGICIDETVT PPQFSIVMEYCELGTLRELLDREKD LTLGKRMVLVLGAARGLYRLHHSEA PELHGKIRSSNFLVTQGYQVKLAGF ELRKTQTSMSLGTTREKTDRVKSTA YLSPQELEDVFYQYDVKSEIYSFGI VLWEIATGDIPFQGCNSEKIRKLVA VKRQQEPLGEDCPSELREIIDECRA HDPSVRPSVDEILKKLSTFSK
• Applications: ELISA; WB-Re; AP; Array
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MLKL mixed lineage kinase domain-like [ Homo sapiens ]
• Official Symbol: MLKL
• Synonyms: MLKL; mixed lineage kinase domain-like; mixed lineage kinase domain-like protein; hMLKL
• Gene ID: 197259
• mRNA Refseq: NM_152649
• Protein Refseq: NP_689862
• MIM: 615153
• UniProt ID: Q8NB16
• Chromosome Location: 16q23.1
• Pathway: DNA damage response (only ATM dependent); TNF signaling pathway
• Function: ATP binding; protein binding; protein complex binding