Recombinant Human KIT, His-tagged
Cat.No. : | KIT-27174TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 544-976 of Human c-Kit containing a V560G mutation, with N-terminal His tag, expressed in a Baculovirus infected Sf9 cell expression system, 50kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Conjugation : | HIS |
Biological activity : | Specific Activity: 115 pmol/min/μg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0 |
Storage : | Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.Contains 5 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 protein kinase domain. |
Gene Name : | KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog [ Homo sapiens ] |
Official Symbol : | KIT |
Synonyms : | KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT, piebald trait; mast/stem cell growth factor receptor Kit; C Kit; CD117; SCFR; |
Gene ID : | 3815 |
mRNA Refseq : | NM_000222 |
Protein Refseq : | NP_000213 |
MIM : | 164920 |
Uniprot ID : | P10721 |
Chromosome Location : | 4q11-q12 |
Pathway : | Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; C-MYB transcription factor network, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | ATP binding; cytokine binding; metal ion binding; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
Kit-2363R | Recombinant Rat Kit Protein, His-tagged | +Inquiry |
KIT-122H | Recombinant Human KIT Protein, Fc-tagged | +Inquiry |
KIT-1138M | Recombinant Mouse KIT protein(Met1-Thr523), His-tagged | +Inquiry |
KIT-2230R | Recombinant Rhesus Macaque KIT Protein, His (Fc)-Avi-tagged | +Inquiry |
KIT-2365H | Recombinant Human KIT Protein, His-tagged | +Inquiry |
◆ Lysates | ||
KIT-463HCL | Recombinant Human KIT cell lysate | +Inquiry |
KIT-001HCL | Recombinant Human KIT cell lysate | +Inquiry |
KIT-1324RCL | Recombinant Rat KIT cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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