| Description : |
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. |
| Protein length : |
338 amino acids |
| Molecular Weight : |
63.250kDa inclusive of tags |
| Source : |
Wheat germ |
| Tissue specificity : |
Cornea and other tissues. |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPE CNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDH IDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKK LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVN LTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP SGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYY LEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETS LPPDMYECLRVANEVTLN |
| Sequence Similarities : |
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.Contains 11 LRR (leucine-rich) repeats.Contains 1 LRRNT domain. |
