Recombinant Human TNNI3
Cat.No. : | TNNI3-27226TH |
Product Overview : | Recombinant human single chain cardiac Troponin I C (ScTnI-C-1) |
- Specification
- Gene Information
- Related Products
Description : | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
Source : | E. coli |
Form : | Liquid |
Storage buffer : | Preservative: 0.025% Sodium AzideConstituents: 50% Glycerol, 12.5μg/ml Aprotinin, 250mM Sodium chloride, 20mM Tris HCl, 2mM Magnesium chloride, 2mM Calcium chloride |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the troponin I family. |
Gene Name : | TNNI3 troponin I type 3 (cardiac) [ Homo sapiens ] |
Official Symbol : | TNNI3 |
Synonyms : | TNNI3; troponin I type 3 (cardiac); troponin I, cardiac; troponin I, cardiac muscle; CMH7; TNNC1; |
Gene ID : | 7137 |
mRNA Refseq : | NM_000363 |
Protein Refseq : | NP_000354 |
MIM : | 191044 |
Uniprot ID : | P19429 |
Chromosome Location : | 19q13.4 |
Pathway : | Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; |
Function : | actin binding; calcium channel inhibitor activity; calcium-dependent protein binding; protein binding; protein domain specific binding; |
Products Types
◆ Recombinant Protein | ||
TNNI3-2254H | Recombinant Human TNNI3 Protein, MYC/DDK-tagged | +Inquiry |
Tnni3-1003H | Active Recombinant Human cTnI Protein | +Inquiry |
TNNI3-2684H | Recombinant Human TNNI3 protein(11-130 aa) | +Inquiry |
TNNI3-871H | Recombinant Human TNNI3 Protein, His-tagged | +Inquiry |
TNNI3-2683H | Recombinant Human TNNI3 protein(11-130 aa), N-SUMO & N-His-tagged | +Inquiry |
◆ Native Protein | ||
TNNI3-223H | Native Human Troponin I Type 3 (Cardiac) | +Inquiry |
TNNI3-221H | Native Human TNNI3 | +Inquiry |
TNNI3-01H | Native Human TNNI3 Protein | +Inquiry |
◆ Lysates | ||
TNNI3-1803HCL | Recombinant Human TNNI3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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