Native Human TNNI3 Protein
Cat.No. : | TNNI3-01H |
Product Overview : | Human Cardiac Troponin C-I-T Complex Protein produced in Human heart tissue. |
- Specification
- Gene Information
- Related Products
Description : | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Troponin I is useful in making a diagnosis of heart failure, and of ischemic heart disease. An elevated level of troponin is also now used as indicator of acute myocardial injury in patients hospitalized with moderate/severe Coronavirus Disease 2019 (COVID-19). Such elevation has also been associated with higher risk of mortality in cardiovascular disease patients hospitalized due to COVID-19. |
Source : | Human cardiac tissue |
Species : | Human |
Form : | Sterile Filtered brown solution. |
Molecular Mass : | 75 kDa |
Storage : | Store at 4 centigrade if entire vial will be used within 2-4 weeks. Store, frozen at -20 centigrade for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
Storage Buffer : | 25 mM TRIS buffer, 0.15 M NaCl, 0.09% sodium azide, pH 7.5. |
Shipping : | Ice Packs |
Gene Name : | TNNI3 troponin I3, cardiac type [ Homo sapiens (human) ] |
Official Symbol : | TNNI3 |
Synonyms : | Troponin I cardiac muscle; Cardiac troponin I; TNNI3; TNNC1; CMH7; RCM1; cTnI; CMD2A; MGC116817; Troponin C slow skeletal and cardiac muscles; TN-C; TNNC1; TNNC; TNC; CMD1Z |
Gene ID : | 7137 |
mRNA Refseq : | NM_000363 |
Protein Refseq : | NP_000354 |
MIM : | 191044 |
UniProt ID : | P19429 |
Products Types
◆ Recombinant Protein | ||
TNNI3-0060H | Recombinant Human TNNI3 Protein | +Inquiry |
TNNI3-9497M | Recombinant Mouse TNNI3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnni3-6569M | Recombinant Mouse Tnni3 Protein, Myc/DDK-tagged | +Inquiry |
TNNI3-2227H | Recombinant Human TNNI3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNNI3-2684H | Recombinant Human TNNI3 protein(11-130 aa) | +Inquiry |
◆ Native Protein | ||
TNNI3-221H | Native Human TNNI3 | +Inquiry |
TNNI3-223H | Native Human Troponin I Type 3 (Cardiac) | +Inquiry |
Tnni3-7423M | Native Mouse Tnni3 Protein | +Inquiry |
◆ Lysates | ||
TNNI3-1803HCL | Recombinant Human TNNI3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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