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Recombinant Human Thymic Stromal Lymphopoietin, Fc Chimera

Cat. No. : TSLP-2147H
Product Overview : Recombinant human mature TSLP(C-terminus fused with murine IgG1 Fc)produced inmammalian cells contains 358 amino acids with predicted molecular weight 40.31KD x 2 (dimer). It contains 13 cysteine and 3 N-link glycosylation sites with increased MW up to 15 KD x2 (dimer).
Description : A recent publication in Nature Immunology demonstrated that human TSLP functions very differently from murine TSLP and plays an important role in regulating TH1 an dTH2 development in dendritic cells. No antibodies are commercially available to characterize its immunoreactivity.
Source : mammalian cells.
Purity : >90%.
Recommended Storage Temperature : -70 °C.
Gene Name : TSLP thymic stromal lymphopoietin [ Homo sapiens ]
Synonyms : Thymic Stromal Lymphopoietin; Thymic stromal lymphopoietin Precursor; TSLP
Gene ID : 85480
mRNA Refseq : NM_033035
Protein Refseq : NP_149024
MIM : 607003
UniProt ID : Q969D9
Chromosome Location : 5q22.1
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : cytokine activity

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