TSLP

  • Official Full Name

    thymic stromal lymphopoietin

  • Overview

    This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. Alternative splicing of this gene results in two transcript variants.
  • Synonyms

    TSLP; Thymic Stromal Lymphopoietin; Thymic stromal lymphopoietin Precursor;

  • Recombinant Proteins
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Cynomolgus
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • Insect cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • C
  • His
  • Fc
  • FC
  • Avi
  • His (Fc)
  • His|T7
  • SUMO
  • LEAF
  • mFc
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TSLP-1389H Active Recombinant Human TSLP protein, His-tagged HEK293 His Tyr 29 - Gln 159
Human TSLP-312H Recombinant Human TSLP protein E.coli N/A 132
Human TSLP-8307H Recombinant Human TSLP N/A
Human TSLP-2147H Recombinant Human Thymic Stromal Lymphopoietin, Fc Chimera Mammalian Cell Fc
Human TSLP-1390H Recombinant Human TSLP Protein, His-tagged Mammalian cells His
Human TSLP-6809H Recombinant Human TSLP protein, His & T7-tagged E.coli His/T7 Tyr29~Gln159 (Accession # Q969D9)
Human TSLP-138H Recombinant Human TSLP Protein, His-tagged, R127A, R130S HEK293 His Met1-Gln159
Human TSLP-0775H Active Recombinant Human TSLP protein, mFc-tagged HEK293 mFc Tyr29-Gln159(R127A,R130A)
Human TSLP-1391H Active Recombinant Human TSLP protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Tyr 29 - Gln 159
Human TSLP-139H Active Recombinant Human TSLP Protein, His-tagged, R127A, R130A HEK293 His Tyr29-Gln159
Human TSLP-499H Recombinant Human TSLP Protein, His-tagged E.coli N-His Met97-Leu156
Human TSLP-372H Recombinant Human TSLP protein, His-tagged HEK293 His 131
Human TSLP-392H Recombinant Human TSLP protein, His-Avi-tagged HEK293 His-Avi It contains Tyr 29 - Gln 159.
Human TSLP-391H Recombinant Human TSLP(R127A, R130A) protein, His-Avi-tagged HEK293 His-Avi It contains Tyr 29 - Gln 159;(R127A, R130A).
Human TSLP-6642H Recombinant Human TSLP Protein (Tyr29-Gln159), C-His tagged Mammalian cells C-His Tyr29-Gln159
Human TSLP-3627H Recombinant Human TSLP protein, His-SUMO-tagged E.coli His-SUMO 29-159aa
Human TSLP-052T Active Recombinant Human TSLP Protein (132 aa) E.coli 132
Human TSLP-500H Recombinant Human TSLP Protein, His&GST-tagged E.coli N-His&GST Met+Tyr29-Lys95
Human TSLP-1377H Recombinant Human TSLP protein(Met1-Gln159), His-tagged, Biotinylated HEK293 C-His Met1-Gln159
Human TSLP-258H Active Recombinant Human TSLP Protein E.coli
Human TSLP-6643H Recombinant Human TSLP Protein (Tyr29-Gln159), C-His tagged E.coli C-His Tyr29-Gln159
Human TSLP-4251H Recombinant Human TSLP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DMABT-H19273 Mouse Anti-TSLP Monoclonal Antibody Mouse LEAF
Human TSLP-4251H-B Recombinant Human TSLP Protein Pre-coupled Magnetic Beads HEK293
Mouse Tslp-736M Active Recombinant Mouse Tslp Protein, His-tagged Mammalian cells His Tyr20-Glu140
Mouse Tslp-202M Active Recombinant Mouse Thymic Stromal Lymphopoietin, His-tagged Insect Cell His
Mouse Tslp-6810M Recombinant Mouse Tslp protein, His-tagged E.coli His Asn21~Ser138
Mouse Tslp-469M Recombinant Mouse Tslp protein, FC-tagged HEK293 FC Gln67-Ser225
Mouse Tslp-468M Recombinant Mouse Tslp, His tagged Human Cell His
Mouse TSLP-1742MCL Recombinant Mouse TSLP cell lysate Human Cell N/A
Mouse Tslp-9677M-B Recombinant Mouse Tslp Protein Pre-coupled Magnetic Beads HEK293
Mouse TSLP-2211M Recombinant Mouse TSLP protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Tyr 20 - Glu 140
Mouse Tslp-501M Recombinant Mouse Tslp Protein, His&SUMO-tagged E.coli N-His&SUMO Met1-Thr90
Mouse Tslp-9677M Recombinant Mouse Tslp Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tslp-502M Recombinant Mouse Tslp Protein, His-tagged E.coli N-His Arg91-Glu140
Mouse Tslp-01M Recombinant Mouse Tslp Protein, His-tagged Insect cell His 20-140
Mouse TSLP-0774M Recombinant Mouse TSLP protein, His-tagged HEK293 His Tyr20-Glu140
Rat Tslp-6811R Recombinant Rat Tslp protein, His-tagged E.coli His Leu75~Ser196
Rat TSLP-0772R Recombinant Rat TSLP protein, His-tagged HEK293 His Tyr18-Ser135
Cynomolgus TSLP-2189C Active Recombinant Cynomolgus TSLP protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Tyr 29 - Gln 159
Cynomolgus TSLP-256C Recombinant Cynomolgus TSLP protein (Met1-Gln159), His-tagged HEK293 His
Cynomolgus TSLP-254C Recombinant Cynomolgus TSLP(Tyr29-Gln159(Gln37Glu)) Protein, C-6*His-tagged E.coli His
Cynomolgus TSLP-0773C Active Recombinant Cynomolgus TSLP protein, His-tagged HEK293 His Tyr29-Gln159(R127A,R130S)
Cynomolgus TSLP-255C Active Recombinant Cynomolgus TSLP protein, His-tagged HEK293 His Tyr 29 - Gln 159
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TSLP Related Articles
  • TSLP Related Research Area

TSLP involved in several pathways and played different roles in them. We selected most pathways TSLP participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSLP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionBMPR2;KIT;GH2;AMHR2;CCL7;CXCL11;CCR3;CD70;CXCL10
Jak-STAT signaling pathwaySOCS6;IL4R;SOCS7;IFNA21;TP-1;IL21;LEPB;FHL1A;IL12RB2

TSLP has several biochemical functions, for example, cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TSLP itself. We selected most functions TSLP had, and list some proteins which have the same functions with TSLP. You can find most of the proteins on our site.

Function Related Protein
cytokine activityAIMP1;FASLG;CCL19A.1;THPO;IFNA5;GREM1;LIF;GRN;MSTNB

TSLP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSLP here. Most of them are supplied by our site. Hope this information will be useful for your research of TSLP.

PRNP; IKBKG

McDermott, AJ; Higdon, KE; et al. The role of Gr-1(+) cells and tumour necrosis factor-alpha signalling during Clostridium difficile colitis in mice. IMMUNOLOGY 144:704-716(2015).
Biedermann, T; Werfel, T; et al. Status quo and prospects for systemic therapy of atopic dermatitis. Biologics ante portas. HAUTARZT 66:108-113(2015).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can WDR5 play a role in non-cancerous diseases? 05/27/2022

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment? 05/08/2020

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

Are there any clinical trials involving WDR5-targeted therapies? 01/15/2020

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases? 02/01/2018

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

How can WDR5 be used as a diagnostic marker for cancer? 11/16/2016

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.

Customer Reviews (3)

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Reviews
04/04/2019

    The TSLP protein offered by the manufacturer excels in its quality and is an excellent match for my experimental requirements.

    02/25/2019

      Their team of experts is readily available to address any queries or concerns I may have regarding the TSLP protein.

      11/22/2016

        Their team of experts is readily available to address any concerns or queries I may have regarding the TSLP protein.

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