GRPR Activated GPCR Internalization Assay Kit
Cat.No. : | Kit-1338 |
Product Overview : | Activated GPCR Internalization cells are engineered to co-an untagged GPCR, Enzyme Acceptor (EA) tagged β-Arrestin, and a ProLink (PK) tag localized to the endosomes. Activation of the GPCR induces β-Arrestin recruitment, followed by internalization of the Receptor/Arrestin-EA complex in PK-tagged endosomes. This forces complementation of the two β-galactosidase enzyme fragments (EA and PK), forming functional enzyme that hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance. |
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Size : | 100 dp(1 x 96-well)/200 dp(2 x 96-well)/1000 dp(10 x 96-well) |
Storage : | Short term (2 weeks): Store in vapor phase of liquid N2 |
Products Types
◆ Recombinant Protein | ||
GRPR-5383H | Recombinant Human GRPR Protein, GST-tagged | +Inquiry |
GRPR-3946M | Recombinant Mouse GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-1802R | Recombinant Rhesus Macaque GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-2377R | Recombinant Rat GRPR Protein, His (Fc)-Avi-tagged | +Inquiry |
GRPR-1981R | Recombinant Rhesus monkey GRPR Protein, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1337 | GRPR U2OS β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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