Active Recombinant Human CALM1 Protein

• Cat.No.: CALM1-01H
• Product Overview: Recombinant Human CALM1 Protein without tag was expressed in E. coli.

Specification

• Description: This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.
• Source: E. coli
• Species: Human
• Form: Lyophilized. Salt-free.
• Bio-activity: Elicits Ca2+-dependent activation of calcineurin (Ca2+/calmodulin-dependent Ser/Thr protein phosphatase 2B, PP-2B) with the same potency and to the same maximum extent as purified native calmodulin.
• Molecular Mass: 16.8 kDa
• Purity: ≥95% (SDS-PAGE)
• Applications: Calmodulin can be used to activate calmodulin-dependent phosphodiesterase, calcineurin, CaM kinases, etc.
• Storage: Long Term Storage at -20 centigrade.
• Reconstitution: Reconstitute in water or an appropriate buffer.
• Shipping: Shipped on Blue Ice

Gene Information

• Gene Name: CALM1 calmodulin 1 [ Homo sapiens (human) ]
• Official Symbol: CALM1
• Synonyms: CALM1; calmodulin 1; caM; CAM2; CAM3; CAMB; CAMC; CAMI; PHKD; CPVT4; DD132; LQT14; PHKD1; CALML2; CAMIII; calmodulin-1; Calmodulin-2; Calmodulin-3; calmodulin 1 (phosphorylase kinase, delta); phosphorylase kinase subunit delta; phosphorylase kinase subunit delta 1; phosphorylase kinase, delta subunit; prepro-calmodulin 1; EC 2.7.11.19
• Gene ID: 801
• mRNA Refseq: NM_006888
• Protein Refseq: NP_008819
• MIM: 114180
• UniProt ID: B4DJ51