Recombinant Human CALM1 Protein

• Cat.No.: CALM1-03H
• Product Overview: Recombinant Full length Human CALM1 Protein (1-148) without tag was exoressed in E. coli.

Specification

• Description: This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.
• Source: E. coli
• Species: Human
• Molecular Mass: 16.6 kDa
• AA Sequence: MADQLTEEQIAEFKEAFSLFDKDGD GTITTKELGTVMRSLGQNPTEAELQ DMINEVDADGNGTIDFPEFLTMMAR KMKDTDSEEEIREAFRVFDKDGNGY ISAAELRHVMTNLGEKLTDEEVDEM IREADIDGDGQVNYEEFVQMMTA
• Purity: > 95% by SDS-PAGE. The protein is observed, in denaturing conditions, as a single band migrating at a molecular weight between 14.4 and 18.4 kDa.
• Storage: At -20 centigrade. The protein is stable at 25 centigrade for several hours. After initial defrost, aliquot the product into individual tubes and refreeze at -20 centigrade.
  Avoid repeated freeze/thaw cycles.
• Concentration: 1.0 mg/mL. The concentration is calculated by the analysis of the absorbance at 280 nm (ε280= 2980 M-1cm-1 calculated).
• Storage Buffer: Tris 20 mM pH 8.0, NaCl 150 mM, CaCl2 2 mM, Complete Protease Inhibitor Cocktail EDTA-free.
• Reconstitution: It is strongly recommended to add 1 tablet of Complete Protease Inhibitor Cocktail EDTA-free in 1000 mL of buffer in case of buffer exchange.
• Shipping: Shipping in Dry Ice

Gene Information

• Gene Name: CALM1 calmodulin 1 [ Homo sapiens (human) ]
• Official Symbol: CALM1
• Synonyms: CALM1; calmodulin 1; caM; CAM2; CAM3; CAMB; CAMC; CAMI; PHKD; CPVT4; DD132; LQT14; PHKD1; CALML2; CAMIII; calmodulin-1; Calmodulin-2; Calmodulin-3; calmodulin 1 (phosphorylase kinase, delta); phosphorylase kinase subunit delta; phosphorylase kinase subunit delta 1; phosphorylase kinase, delta subunit; prepro-calmodulin 1; EC 2.7.11.19
• Gene ID: 801
• mRNA Refseq: NM_006888
• Protein Refseq: NP_008819
• MIM: 114180
• UniProt ID: B4DJ51