Species : |
Human |
Source : |
E.coli |
Protein Length : |
1-148 a.a. |
Description : |
This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia. |
Molecular Mass : |
16.6 kDa |
AA Sequence : |
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTA |
Purity : |
> 95% by SDS-PAGE. The protein is observed, in denaturing conditions, as a single band migrating at a molecular weight between 14.4 and 18.4 kDa. |
Storage : |
At -20 centigrade. The protein is stable at 25 centigrade for several hours. After initial defrost, aliquot the product into individual tubes and refreeze at -20 centigrade. Avoid repeated freeze/thaw cycles. |
Concentration : |
1.0 mg/mL. The concentration is calculated by the analysis of the absorbance at 280 nm (ε280= 2980 M-1cm-1 calculated). |
Storage Buffer : |
Tris 20 mM pH 8.0, NaCl 150 mM, CaCl2 2 mM, Complete Protease Inhibitor Cocktail EDTA-free. |
Reconstitution : |
It is strongly recommended to add 1 tablet of Complete Protease Inhibitor Cocktail EDTA-free in 1000 mL of buffer in case of buffer exchange. |
Shipping : |
Shipping in Dry Ice |
Full Length : |
Full L. |