CALM3
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Official Full Name
calmodulin 3 (phosphorylase kinase, delta) -
Overview
Calmodulin is a protein that in humans is encoded by the CALM3 gene. -
Synonyms
CALM3;calmodulin 3 (phosphorylase kinase, delta);calmodulin;PHKD;CALM;CALM2;CALML2;CAM;CAM1;CAM2;CAM3;CAMB;CAMC;CAMIII;PHKD3;CALM1
Recombinant Proteins
- Rat
- Mouse
- Human
- Bovine
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- Bovine Brain
- His
- Non
- GST
- Avi
- Fc
- DDK
- Myc
Involved Pathway
CALM3 involved in several pathways and played different roles in them. We selected most pathways CALM3 participated on our site, such as Ras signaling pathway,Rap signaling pathway,Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CALM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alzheimers disease | COX4I2,Atp5g2,UQCRC2,NDUFA5,APH1C,SDHA,NDUFB4,NDUFC1,NDUFS2,CDK5R1 |
| Long-term potentiation | CALM4,GRIN2C,CALML5,CALML3,CAMK2D,ITPR3,GRIA1,ARAF,RAP1A,RAP1B |
| Ras signaling pathway | PGF,FGF1,GNGT1,BCL2L1,PLA2G1B,FIGF,FGF3,FGF12,Kitl,ETS1 |
| cAMP signaling pathway | TNNI3,HTR4,BRAF,PDE4D,PLN,ATP1B3,AKT1,HCAR2,CAMK4,PPP1CC |
| Phototransduction | GNAT1,PDE6B,CALML5,GRK7B,CALM2,GRK7A,CALM1A,RGS9B,OPN1MW4,GNGT1 |
| Vascular smooth muscle contraction | GNA15.1,PLA2G12A,PPP1R12C,PLCB3,CALM2B,PLA2G2A,PLA2G12B,CACNA1DA,GNA13A,CALM |
| Inflammatory mediator regulation of TRP channels | CALML5,MAPK8,PRKCQ,PIK3CA,CAMK2D,CAMK2B,HTR2A,PPP1CC,ACCN5,TRPA1 |
| Phosphatidylinositol signaling system | PI4K2B,CALM3A,CALM3B,PIK3CG,PTENB,IP6K3,INPP4A,PI4KA,PLCD1B,MTMR2 |
| Renin secretion | GNAI3,ITPR1,CLCA3,CLCA1,PLCB1,PTGER2,GNAS,PPP3CB,PLCB2,PPP3CA |
Protein Function
CALM3 has several biochemical functions, for example, N-terminal myristoylation domain binding,adenylate cyclase binding,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CALM3 itself. We selected most functions CALM3 had, and list some proteins which have the same functions with CALM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SELPLG,PIAS1,EFHC1,STRN,GPN1,SIAH1A,KIAA1191,CDK20,TRIM17,ITM2A |
| calcium-dependent protein binding | ANXA3,SYN1,ANXA1,RBM22,SEC31A,NELF,MBL1,TNNI3,VPS37B,S100PBP |
| titin binding | CAPN3,CALM,TCAP,CAMK2D,ACTN2,ANKRD1,MYBPC3,OBSCN,SLC14A2,CALM2 |
| N-terminal myristoylation domain binding | CALM,CALM2,CALM1 |
| adenylate cyclase binding | CALM1,AKAP5,AKAP12,AKAP6,CHRNA7,ADRB2,CALM2,ADCYAP1R1 |
| nitric-oxide synthase regulator activity | HSP90AA1,ESR1,CALM2,CALM1,AKT1,HSP90AB1,HSP90AA1.1 |
| ion channel binding | AP2M1,NOS1,YWHAE,PIRT,KCNH1,CAV3,KCND3,ACTN3,SUMO1,SRC |
| phospholipase binding | ARHGAP6,Pla2r1,SERPINB1A,CALM2,WAS,PTPN11,PARK2,CALM,SELE,PRKCZ |
| type 3 metabotropic glutamate receptor binding | CALM2,CALM1 |
Interacting Protein
CALM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CALM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CALM3.
cya;CCP110;EGFR
CALM3 Related Signal Pathway
Resources
Gene Families
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References
- Priddy, TS; Price, ES; et al. Single molecule analyses of the conformational substates of calmodulin bound to the phosphorylase kinase complex. PROTEIN SCIENCE 16:1017-1023(2007).
- Priddy, TS; Macdonald, BA; et al. Ca2+-induced structural changes in phosphorylase kinase detected by small-angle X-ray scattering. PROTEIN SCIENCE 14:1039-1048(2005).
