Recombinant Human CHEK1 Protein, MYC/DDK-tagged
Cat.No. : | CHEK1-3217H |
Product Overview : | Recombinant Human CHEK1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 54.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | CHEK1 checkpoint kinase 1 [ Homo sapiens ] |
Official Symbol : | CHEK1 |
Synonyms : | CHK1; CHK1 |
Gene ID : | 1111 |
mRNA Refseq : | NM_001114121 |
Protein Refseq : | NP_001107593 |
MIM : | 603078 |
UniProt ID : | O14757 |
Products Types
◆ Recombinant Protein | ||
CHEK1-1220H | Active Recombinant Human CHEK1 Protein, GST-His-Tagged | +Inquiry |
Chek1-884M | Recombinant Mouse Chek1 Protein, MYC/DDK-tagged | +Inquiry |
CHEK1-595H | Recombinant Human CHEK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CHEK1-1186H | Recombinant Human CHEK1 Protein (A2-T476), Tag Free | +Inquiry |
CHEK1-1187H | Recombinant Human CHEK1 Protein (A2-T476), GST tagged | +Inquiry |
◆ Lysates | ||
CHEK1-001MCL | Recombinant Mouse CHEK1 cell lysate | +Inquiry |
CHEK1-438HCL | Recombinant Human CHEK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket