| Description : |
This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
52.9 kDa |
| AA Sequence : |
MSGSSARSSHLSQPVVKSVLVYRNG DPFYAGRRVVIHEKKVSSFEVFLKE VTGGVQAPFGAVRNIYTPRTDHRIR KLDQIQSGGNYVAGGQEAFKKLNYL DIGEIKKRPMEVVNTEVKPVIHSRI NVSARFRKPLQEPCTIFLIANGDLI NPASRLLIPRKTLNQWDHVLQMVTE KITLRSGAVHRLYTLEGKLVESGAE LENGQFYVAVGRDKFKKLPYGELLF DKSTMRRPFGQKASSLPPIVGSRKS KGSGNDRHSKSTVGSSDNSSPQPLK RKGKKEDVNSEKLTKLKQNVKLKNS QETIPNSDEGIFKAGAERSETRGAA EVQEDEDTQVEVPVDQRPAEIVDEE EDGEKANKDAEQKEDFSGMNGDLEE EGGREATDAPEQVEEILDHSEQQAR PARVNGGTDEENGEELQQVNNELQL VLDKERKSQGAGSGQDEADVDPQRP PRPEVKITSPEENENNQQNKDYAAV ATRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
